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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Oct 2000 Volume 17 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Oct 2000 Volume 17 Issue 4

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Article

Induction of apoptosis by dietary polyunsaturated fatty acids in human leukemic cells is not associated with DNA fragmentation.

  • Authors:
    • L C Chiu
    • J M Wan
    • V E Ooi
  • View Affiliations / Copyright

    Affiliations: Department of Biology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, P.R. China. chimingchiu@cuhk.edu.hk
  • Pages: 789-885
    |
    Published online on: October 1, 2000
       https://doi.org/10.3892/ijo.17.4.789
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Abstract

Apoptosis is important in anticancer strategy. In this study, bivariate annexin V/PI flow cytometry showed that dietary polyunsaturated fatty acids, arachidonic acid (AA) and eicosapentaenoic acid (EPA), induced apoptosis in human leukemic HL-60 but not K-562 cells. Results from DNA-PI flow cytometry and TUNEL flow cytometry illustrated that neither AA nor EPA induced DNA fragmentation in the leukemic cells. These findings suggested that the AA- and EPA-induced apoptosis might not associate with endonucleases activation, and DNA fragmentation could not be used as a sole criterion to identify apoptotic cells.

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Copy and paste a formatted citation
Spandidos Publications style
Chiu L, Wan J and Ooi V: Induction of apoptosis by dietary polyunsaturated fatty acids in human leukemic cells is not associated with DNA fragmentation.. Int J Oncol 17: 789-885, 2000.
APA
Chiu, L., Wan, J., & Ooi, V. (2000). Induction of apoptosis by dietary polyunsaturated fatty acids in human leukemic cells is not associated with DNA fragmentation.. International Journal of Oncology, 17, 789-885. https://doi.org/10.3892/ijo.17.4.789
MLA
Chiu, L., Wan, J., Ooi, V."Induction of apoptosis by dietary polyunsaturated fatty acids in human leukemic cells is not associated with DNA fragmentation.". International Journal of Oncology 17.4 (2000): 789-885.
Chicago
Chiu, L., Wan, J., Ooi, V."Induction of apoptosis by dietary polyunsaturated fatty acids in human leukemic cells is not associated with DNA fragmentation.". International Journal of Oncology 17, no. 4 (2000): 789-885. https://doi.org/10.3892/ijo.17.4.789
Copy and paste a formatted citation
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Spandidos Publications style
Chiu L, Wan J and Ooi V: Induction of apoptosis by dietary polyunsaturated fatty acids in human leukemic cells is not associated with DNA fragmentation.. Int J Oncol 17: 789-885, 2000.
APA
Chiu, L., Wan, J., & Ooi, V. (2000). Induction of apoptosis by dietary polyunsaturated fatty acids in human leukemic cells is not associated with DNA fragmentation.. International Journal of Oncology, 17, 789-885. https://doi.org/10.3892/ijo.17.4.789
MLA
Chiu, L., Wan, J., Ooi, V."Induction of apoptosis by dietary polyunsaturated fatty acids in human leukemic cells is not associated with DNA fragmentation.". International Journal of Oncology 17.4 (2000): 789-885.
Chicago
Chiu, L., Wan, J., Ooi, V."Induction of apoptosis by dietary polyunsaturated fatty acids in human leukemic cells is not associated with DNA fragmentation.". International Journal of Oncology 17, no. 4 (2000): 789-885. https://doi.org/10.3892/ijo.17.4.789
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