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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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July 2001 Volume 19 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Medicine International

An International Open Access Journal Devoted to General Medicine.

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Article

Non-Hodgkin's lymphoma presenting with spinal involvement: the Sheffield Lymphoma Group experience (1970-2000)

  • Authors:
    • H. Y. Ching
    • J. M. Horsman
    • C. R. Radstone
    • H. Hancock
    • W. R. Timperley
    • B. W. Hancock

  • View Affiliations / Copyright

    Affiliations: YCR Academic Unit of Oncology, Weston Park Hospital, Sheffield, UK
  • Pages: 149-156
    |
    Published online on: July 1, 2001
       https://doi.org/10.3892/ijo.19.1.149
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Abstract

Spinal non-Hodgkin's lymphoma is rare. We retrospectively reviewed the clinical and histopathologic records of 39 consecutive patients referred to the Sheffield Lymphoma Group from 1970 to 2000 and analysed the prognostic differences between localised (stage IE and IIE) and secondary (stage III and IV) spinal non-Hodgkin's lymphoma (S-NHL) patients. Forty-five percent of all patients were over 60 years old. More patients were male (58%); presented with stage IE and IIE (63%), mostly of intermediate/high grade histology (74%); over a third had symptoms; nearly a third (11 patients) were paraplegic and 14 had sphincter dysfunction at diagnosis. The overall survival of all patients was 39% at 5 years (median 24.7 months), whilst that of localised S-NHL was 51% (median 89.7 months). Univariate analysis showed better survival for patients with good mobility status at presentation (p<0.0l) and complete response to initial treatment (p<0.00l). In primary S-NHL, histology (p<0.05) significantly influenced overall survival. In conclusion, disease is frequently locally advanced at presentation with aggressive histologic grade: thorough staging should always be performed to exclude widespread disease. Good mobility status predicts for good survival outcome. Optimal treatment is still uncertain.

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Copy and paste a formatted citation
Spandidos Publications style
Ching HY, Horsman JM, Radstone CR, Hancock H, Timperley WR and Hancock BW: Non-Hodgkin's lymphoma presenting with spinal involvement: the Sheffield Lymphoma Group experience (1970-2000). Int J Oncol 19: 149-156, 2001.
APA
Ching, H.Y., Horsman, J.M., Radstone, C.R., Hancock, H., Timperley, W.R., & Hancock, B.W. (2001). Non-Hodgkin's lymphoma presenting with spinal involvement: the Sheffield Lymphoma Group experience (1970-2000). International Journal of Oncology, 19, 149-156. https://doi.org/10.3892/ijo.19.1.149
MLA
Ching, H. Y., Horsman, J. M., Radstone, C. R., Hancock, H., Timperley, W. R., Hancock, B. W."Non-Hodgkin's lymphoma presenting with spinal involvement: the Sheffield Lymphoma Group experience (1970-2000)". International Journal of Oncology 19.1 (2001): 149-156.
Chicago
Ching, H. Y., Horsman, J. M., Radstone, C. R., Hancock, H., Timperley, W. R., Hancock, B. W."Non-Hodgkin's lymphoma presenting with spinal involvement: the Sheffield Lymphoma Group experience (1970-2000)". International Journal of Oncology 19, no. 1 (2001): 149-156. https://doi.org/10.3892/ijo.19.1.149
Copy and paste a formatted citation
x
Spandidos Publications style
Ching HY, Horsman JM, Radstone CR, Hancock H, Timperley WR and Hancock BW: Non-Hodgkin's lymphoma presenting with spinal involvement: the Sheffield Lymphoma Group experience (1970-2000). Int J Oncol 19: 149-156, 2001.
APA
Ching, H.Y., Horsman, J.M., Radstone, C.R., Hancock, H., Timperley, W.R., & Hancock, B.W. (2001). Non-Hodgkin's lymphoma presenting with spinal involvement: the Sheffield Lymphoma Group experience (1970-2000). International Journal of Oncology, 19, 149-156. https://doi.org/10.3892/ijo.19.1.149
MLA
Ching, H. Y., Horsman, J. M., Radstone, C. R., Hancock, H., Timperley, W. R., Hancock, B. W."Non-Hodgkin's lymphoma presenting with spinal involvement: the Sheffield Lymphoma Group experience (1970-2000)". International Journal of Oncology 19.1 (2001): 149-156.
Chicago
Ching, H. Y., Horsman, J. M., Radstone, C. R., Hancock, H., Timperley, W. R., Hancock, B. W."Non-Hodgkin's lymphoma presenting with spinal involvement: the Sheffield Lymphoma Group experience (1970-2000)". International Journal of Oncology 19, no. 1 (2001): 149-156. https://doi.org/10.3892/ijo.19.1.149
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