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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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March 1993 Volume 2 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
March 1993 Volume 2 Issue 3

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Article

MALIGNANT GLIOMAS TREATED WITH SPLIT COURSE RADIOTHERAPY PLUS CHEMOTHERAPY

  • Authors:
    • K MINEURA
    • K WATANABE
    • M KOWADA
    • T KATO

  • View Affiliations / Copyright

    Affiliations: AKITA UNIV HOSP,DEPT RADIOL,AKITA,JAPAN.
  • Pages: 457-461
    |
    Published online on: March 1, 1993
       https://doi.org/10.3892/ijo.2.3.457
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Abstract

Twenty-five adult patients with supratentorial malignant gliomas (malignant astrocytoma and glioblastoma multiforme) verified histologically from 1979 to 1986 postoperatively received combined modalities of split course radiotherapy (sRT), nimustine hydrochloride (ACNU), and tegafur (FT). The initial course of radiation consisted of 30 Gy whole brain in 15 fractions five days a week. After a one-week interruption, local radiation with a limited field including a tumor and a margin was boosted to a total dose of about 50-60 Gy. The results were compared with historical control comprising malignant gliomas which received continuous course of radiotherapy (cRT) with or without other chemotherapy before 1979 and after 1986. The median survival time (MST) of malignant gliomas was 18 months for sRT plus chemotherapy, 12 months for cRT alone, and 13 months for cRT plus chemotherapy. No differences between the Kaplan-Meier survival curves were significant by the generalized Wilcoxon test. Tumor histology, Karnofsky performance status, and patient age related well with survival.

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Copy and paste a formatted citation
Spandidos Publications style
MINEURA K, WATANABE K, KOWADA M and KATO T: MALIGNANT GLIOMAS TREATED WITH SPLIT COURSE RADIOTHERAPY PLUS CHEMOTHERAPY. Int J Oncol 2: 457-461, 1993.
APA
MINEURA, K., WATANABE, K., KOWADA, M., & KATO, T. (1993). MALIGNANT GLIOMAS TREATED WITH SPLIT COURSE RADIOTHERAPY PLUS CHEMOTHERAPY. International Journal of Oncology, 2, 457-461. https://doi.org/10.3892/ijo.2.3.457
MLA
MINEURA, K., WATANABE, K., KOWADA, M., KATO, T."MALIGNANT GLIOMAS TREATED WITH SPLIT COURSE RADIOTHERAPY PLUS CHEMOTHERAPY". International Journal of Oncology 2.3 (1993): 457-461.
Chicago
MINEURA, K., WATANABE, K., KOWADA, M., KATO, T."MALIGNANT GLIOMAS TREATED WITH SPLIT COURSE RADIOTHERAPY PLUS CHEMOTHERAPY". International Journal of Oncology 2, no. 3 (1993): 457-461. https://doi.org/10.3892/ijo.2.3.457
Copy and paste a formatted citation
x
Spandidos Publications style
MINEURA K, WATANABE K, KOWADA M and KATO T: MALIGNANT GLIOMAS TREATED WITH SPLIT COURSE RADIOTHERAPY PLUS CHEMOTHERAPY. Int J Oncol 2: 457-461, 1993.
APA
MINEURA, K., WATANABE, K., KOWADA, M., & KATO, T. (1993). MALIGNANT GLIOMAS TREATED WITH SPLIT COURSE RADIOTHERAPY PLUS CHEMOTHERAPY. International Journal of Oncology, 2, 457-461. https://doi.org/10.3892/ijo.2.3.457
MLA
MINEURA, K., WATANABE, K., KOWADA, M., KATO, T."MALIGNANT GLIOMAS TREATED WITH SPLIT COURSE RADIOTHERAPY PLUS CHEMOTHERAPY". International Journal of Oncology 2.3 (1993): 457-461.
Chicago
MINEURA, K., WATANABE, K., KOWADA, M., KATO, T."MALIGNANT GLIOMAS TREATED WITH SPLIT COURSE RADIOTHERAPY PLUS CHEMOTHERAPY". International Journal of Oncology 2, no. 3 (1993): 457-461. https://doi.org/10.3892/ijo.2.3.457
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