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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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June 1993 Volume 2 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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June 1993 Volume 2 Issue 6

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Article

BINDING OF MITOCHONDRIAL AND NUCLEAR PROTEINS FROM MOUSE AND HUMAN-CELLS TO GRE-LIKE ELEMENTS OF MOUSE MITOCHONDRIAL-DNA

  • Authors:
    • C TSIRIYOTIS
    • DA SPANDIDOS
    • CE SEKERIS

  • View Affiliations / Copyright

    Affiliations: NATL HELLEN RES FDN,INST BIOL RES & BIOTECHNOL,48 VAS CONSTANTINOU AVE,GR-11635 ATHENS,GREECE. UNIV CRETE,SCH MED,IRAKLION,GREECE. UNIV ATHENS,DEPT BIOL,ATHENS,GREECE.
  • Pages: 947-952
    |
    Published online on: June 1, 1993
       https://doi.org/10.3892/ijo.2.6.947
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Abstract

In the context of the hypothesis that the mitochondria represent primary sites of steroid hormone action we have evaluated the possible role of two nucleotide sequences partially homologous to Glucocorticoid Responsive Elements (GREs) present in the cytochrome oxidase subunit I gene of mouse and human mitochondrial DNA, as binding sites for mitochondrial and nuclear regulatory protein(s). Using a gel retardation assay, we examined whether proteins contained in mitochondrial and nuclear extracts from untreated and dexamethasone treated MCF7 and LATK- cell lines bind to these oligonucleotides. Both the mitochondrial and nuclear extracts from these cell lines contain protein(s) that bind to the oligonucleotides, as well as to the GRE of the human metallothionein II(A) promoter, binding which was considerably enhanced when the extracts were derived from cells previously treated with dexamethasone.

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Copy and paste a formatted citation
Spandidos Publications style
TSIRIYOTIS C, SPANDIDOS D and SEKERIS C: BINDING OF MITOCHONDRIAL AND NUCLEAR PROTEINS FROM MOUSE AND HUMAN-CELLS TO GRE-LIKE ELEMENTS OF MOUSE MITOCHONDRIAL-DNA. Int J Oncol 2: 947-952, 1993.
APA
TSIRIYOTIS, C., SPANDIDOS, D., & SEKERIS, C. (1993). BINDING OF MITOCHONDRIAL AND NUCLEAR PROTEINS FROM MOUSE AND HUMAN-CELLS TO GRE-LIKE ELEMENTS OF MOUSE MITOCHONDRIAL-DNA. International Journal of Oncology, 2, 947-952. https://doi.org/10.3892/ijo.2.6.947
MLA
TSIRIYOTIS, C., SPANDIDOS, D., SEKERIS, C."BINDING OF MITOCHONDRIAL AND NUCLEAR PROTEINS FROM MOUSE AND HUMAN-CELLS TO GRE-LIKE ELEMENTS OF MOUSE MITOCHONDRIAL-DNA". International Journal of Oncology 2.6 (1993): 947-952.
Chicago
TSIRIYOTIS, C., SPANDIDOS, D., SEKERIS, C."BINDING OF MITOCHONDRIAL AND NUCLEAR PROTEINS FROM MOUSE AND HUMAN-CELLS TO GRE-LIKE ELEMENTS OF MOUSE MITOCHONDRIAL-DNA". International Journal of Oncology 2, no. 6 (1993): 947-952. https://doi.org/10.3892/ijo.2.6.947
Copy and paste a formatted citation
x
Spandidos Publications style
TSIRIYOTIS C, SPANDIDOS D and SEKERIS C: BINDING OF MITOCHONDRIAL AND NUCLEAR PROTEINS FROM MOUSE AND HUMAN-CELLS TO GRE-LIKE ELEMENTS OF MOUSE MITOCHONDRIAL-DNA. Int J Oncol 2: 947-952, 1993.
APA
TSIRIYOTIS, C., SPANDIDOS, D., & SEKERIS, C. (1993). BINDING OF MITOCHONDRIAL AND NUCLEAR PROTEINS FROM MOUSE AND HUMAN-CELLS TO GRE-LIKE ELEMENTS OF MOUSE MITOCHONDRIAL-DNA. International Journal of Oncology, 2, 947-952. https://doi.org/10.3892/ijo.2.6.947
MLA
TSIRIYOTIS, C., SPANDIDOS, D., SEKERIS, C."BINDING OF MITOCHONDRIAL AND NUCLEAR PROTEINS FROM MOUSE AND HUMAN-CELLS TO GRE-LIKE ELEMENTS OF MOUSE MITOCHONDRIAL-DNA". International Journal of Oncology 2.6 (1993): 947-952.
Chicago
TSIRIYOTIS, C., SPANDIDOS, D., SEKERIS, C."BINDING OF MITOCHONDRIAL AND NUCLEAR PROTEINS FROM MOUSE AND HUMAN-CELLS TO GRE-LIKE ELEMENTS OF MOUSE MITOCHONDRIAL-DNA". International Journal of Oncology 2, no. 6 (1993): 947-952. https://doi.org/10.3892/ijo.2.6.947
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