Laparoscopic ethanol injection therapy for hepatocellular carcinoma

  • Authors:
    • Hiroshi Okano
    • Katsuya Shiraki
    • Hidekazu Inoue
    • Takenari Yamanaka
    • Masatoshi Deguchi
    • Kazushi Sugimoto
    • Takahisa Sakai
    • Shigeru Ohmori
    • Kazumoto Murata
    • Takeshi Nakano
  • View Affiliations

  • Published online on: February 1, 2002     https://doi.org/10.3892/ijo.20.2.267
  • Pages: 267-271
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Abstract

Ethanol injection into HCC tumors is an effective therapy and percutaneous ethanol injection therapy (PEIT) is performed on many HCC patients. However, there are cases in which PEIT becomes difficult because the HCC could not be detected by ultrasonography or the tumor is located in an area where it is impossible to perform PEIT. Nine patients with HCC underwent laparoscopic ethanol injection therapy (LEIT) in our institution. Their tumors were located on the liver surface and could be visualized by laparoscopic examination. Ethanol injection was performed under laparoscopic direct visualization. The total injected ethanol volume required ranged from 4 to 15 ml and in most cases both tumor size and α-fetoprotein (AFP) levels decreased after LEIT. Three cases showed a transient complication of abdominal pain or/and portal vein damage. Other severe complications were not observed. All cases required additional therapies, including transcatheter arterial chemoembolization (TAE) or PEIT to complete the tumor necrosis. In conclusion, LEIT is a safe and effective therapy for HCC located on the liver surface, but should be combined with other therapies to facilitate its effect against HCC.

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February 2002
Volume 20 Issue 2

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Okano H, Shiraki K, Inoue H, Yamanaka T, Deguchi M, Sugimoto K, Sakai T, Ohmori S, Murata K, Nakano T, Nakano T, et al: Laparoscopic ethanol injection therapy for hepatocellular carcinoma. Int J Oncol 20: 267-271, 2002
APA
Okano, H., Shiraki, K., Inoue, H., Yamanaka, T., Deguchi, M., Sugimoto, K. ... Nakano, T. (2002). Laparoscopic ethanol injection therapy for hepatocellular carcinoma. International Journal of Oncology, 20, 267-271. https://doi.org/10.3892/ijo.20.2.267
MLA
Okano, H., Shiraki, K., Inoue, H., Yamanaka, T., Deguchi, M., Sugimoto, K., Sakai, T., Ohmori, S., Murata, K., Nakano, T."Laparoscopic ethanol injection therapy for hepatocellular carcinoma". International Journal of Oncology 20.2 (2002): 267-271.
Chicago
Okano, H., Shiraki, K., Inoue, H., Yamanaka, T., Deguchi, M., Sugimoto, K., Sakai, T., Ohmori, S., Murata, K., Nakano, T."Laparoscopic ethanol injection therapy for hepatocellular carcinoma". International Journal of Oncology 20, no. 2 (2002): 267-271. https://doi.org/10.3892/ijo.20.2.267