Laparoscopic ethanol injection therapy for hepatocellular carcinoma

Okano,Hiroshi; Shiraki,Katsuya; Inoue,Hidekazu; Yamanaka,Takenari; Deguchi,Masatoshi; Sugimoto,Kazushi; Sakai,Takahisa; Ohmori,Shigeru; Murata,Kazumoto; Nakano,Takeshi

doi:10.3892/ijo.20.2.267

February 2002 Volume 20 Issue 2

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February 2002 Volume 20 Issue 2

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Article

Laparoscopic ethanol injection therapy for hepatocellular carcinoma

Authors:
- Hiroshi Okano
- Katsuya Shiraki
- Hidekazu Inoue
- Takenari Yamanaka
- Masatoshi Deguchi
- Kazushi Sugimoto
- Takahisa Sakai
- Shigeru Ohmori
- Kazumoto Murata
- Takeshi Nakano
View Affiliations / Copyright

Affiliations: First Department of Internal Medicine, Mie University School of Medicine, Tsu 514-8507, Japan
Pages: 267-271
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Published online on: February 1, 2002

https://doi.org/10.3892/ijo.20.2.267
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Abstract

Ethanol injection into HCC tumors is an effective therapy and percutaneous ethanol injection therapy (PEIT) is performed on many HCC patients. However, there are cases in which PEIT becomes difficult because the HCC could not be detected by ultrasonography or the tumor is located in an area where it is impossible to perform PEIT. Nine patients with HCC underwent laparoscopic ethanol injection therapy (LEIT) in our institution. Their tumors were located on the liver surface and could be visualized by laparoscopic examination. Ethanol injection was performed under laparoscopic direct visualization. The total injected ethanol volume required ranged from 4 to 15 ml and in most cases both tumor size and α-fetoprotein (AFP) levels decreased after LEIT. Three cases showed a transient complication of abdominal pain or/and portal vein damage. Other severe complications were not observed. All cases required additional therapies, including transcatheter arterial chemoembolization (TAE) or PEIT to complete the tumor necrosis. In conclusion, LEIT is a safe and effective therapy for HCC located on the liver surface, but should be combined with other therapies to facilitate its effect against HCC.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Laparoscopic ethanol injection therapy for hepatocellular carcinoma

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