[Corrigendum] Functional analysis of Zyxin in cell migration and invasive potential of oral squamous cell carcinoma cells

Yamamura,Michiyo; Noguchi,Kazuma; Nakano,Yoshiro; Segawa,Emi; Zushi,Yusuke; Takaoka,Kazuki; Kishimoto,Hiromitsu; Hashimoto-Tamaoki,Tomoko; Urade,Masahiro

doi:10.3892/ijo.2016.3702

November-2016 Volume 49 Issue 5

Full Size Image

Cover Legend PDF

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

November-2016 Volume 49 Issue 5

Full Size Image

Cover Legend PDF

Correction Open Access

[Corrigendum] Functional analysis of Zyxin in cell migration and invasive potential of oral squamous cell carcinoma cells

Authors:
- Michiyo Yamamura
- Kazuma Noguchi
- Yoshiro Nakano
- Emi Segawa
- Yusuke Zushi
- Kazuki Takaoka
- Hiromitsu Kishimoto
- Tomoko Hashimoto-Tamaoki
- Masahiro Urade
View Affiliations / Copyright

Affiliations: Department of Oral and Maxillofacial Surgery, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan, Department of Genetics, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan

Copyright: © Yamamura et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 2188-2188
|
Published online on: September 22, 2016

https://doi.org/10.3892/ijo.2016.3702
Expand metrics +

Article

Functional analysis of Zyxin in cell migration and invasive potential of oral squamous cell carcinoma cells

MICHIYO YAMAMURA, KAZUMA NOGUCHI, YOSHIRO NAKANO, EMI SEGAWA, YUSUKE ZUSHI, KAZUKI TAKAOKA, HIROMITSU KISHIMOTO, TOMOKO HASHIMOTO-TAMAOKI and MASAHIRO URADE

Int J Oncol 42: 873-880, 2013; DOI: 10.3892/ijo.2013.1761

Following the publication of this article, an interested reader drew to our attention an anomaly associated with the presentation of Figs. 2 and 3. Essentially, there was a direct duplication of certain of the western blotting data between Fig. 2 (the E-cadherin and Actin data) and Fig. 3C (the Zyxin and Actin data).

Figure 3

(A and B) Immunocytochemical analysis of cell morphological changes induced by Zyxin siRNA treatment. Blue, nuclear (DAPI); red, actin (phalloidin); green, Zyxin (FITC). Note that Zyxin was localized at adhesion plaques and some overlapped with actin stress fibers (arrow). Treatment with Zyxin siRNA resulted in reduced expression of Zyxin and morphological changes from spindle to polygonal shape. (C) Inhibition of Zyxin expression by Zyxin siRNA treatment did not alter LPP or TRIP-6 expression.

After having re-examined our original data, we realize that we inadvertently duplicated the data from Fig. 2 in Fig. 3C (the Zyxin and Actin data).

A corrected version of Fig. 3C (containing the true Zyxin and Actin data), and, by natural process, also of Fig. 6, are presented below, in which the Zyxin data in Figs. 3C and 6 are now correctly shown. Since the Zyxin data was a control for the siZyxin knockout of HOC313, this error did not affect the results of the Rho family analysis in this study. We sincerely apologize for this mistake, and thank the reader of our article who drew this matter to our attention. Furthermore, we regret any inconvenience this mistake has caused.

Figure 6

Analysis of Rho family proteins by western blotting. Rho family small GTPases involved in cell migration and invasion, such as RhoA, Rac1 and CDC42, were examined. There was no significant difference in expression of RhoA, but expressions of Rac1 and CDC42 were slightly reduced in Zyxin siRNA-treated cells.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

[Corrigendum] Functional analysis of Zyxin in cell migration and invasive potential of oral squamous cell carcinoma cells

This article is mentioned in:

Article

Figure 3

Figure 6

Figure 3

Figure 6

Related Articles