How to best classify breast cancer: Conventional and novel classifications (Review)

  • Authors:
    • Emmanuelle Charafe-Jauffret
    • Christophe Ginestier
    • Florence Monville
    • Samira Fekairi
    • Jocelyne Jacquemier
    • Daniel Birnbaum
    • François Bertucci
  • View Affiliations

  • Published online on: November 1, 2005     https://doi.org/10.3892/ijo.27.5.1307
  • Pages: 1307-1313
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Abstract

Breast cancer is a complex disease and different classifications, mostly based on clinical and pathological features, have been used for guiding the management of patients. Most of them fail to reflect breast cancer heterogeneity, which could be the reason why the treatment fails in approximately 30% of cases. Emerging molecular studies based on gene expression profiling using DNA microarrays have defined new molecular subtypes of breast cancer associated with the cell-of-origin distinction. Thus, breast cancer has been divided into five subgroups with distinct biological features and clinical outcomes. We have tried here to confront the conventional existing classifications with this new molecular taxonomy. It is likely that using all types of classification together will help in the management of breast cancer.

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November 2005
Volume 27 Issue 5

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Charafe-Jauffret E, Ginestier C, Monville F, Fekairi S, Jacquemier J, Birnbaum D and Bertucci F: How to best classify breast cancer: Conventional and novel classifications (Review). Int J Oncol 27: 1307-1313, 2005
APA
Charafe-Jauffret, E., Ginestier, C., Monville, F., Fekairi, S., Jacquemier, J., Birnbaum, D., & Bertucci, F. (2005). How to best classify breast cancer: Conventional and novel classifications (Review). International Journal of Oncology, 27, 1307-1313. https://doi.org/10.3892/ijo.27.5.1307
MLA
Charafe-Jauffret, E., Ginestier, C., Monville, F., Fekairi, S., Jacquemier, J., Birnbaum, D., Bertucci, F."How to best classify breast cancer: Conventional and novel classifications (Review)". International Journal of Oncology 27.5 (2005): 1307-1313.
Chicago
Charafe-Jauffret, E., Ginestier, C., Monville, F., Fekairi, S., Jacquemier, J., Birnbaum, D., Bertucci, F."How to best classify breast cancer: Conventional and novel classifications (Review)". International Journal of Oncology 27, no. 5 (2005): 1307-1313. https://doi.org/10.3892/ijo.27.5.1307