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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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July 1993 Volume 3 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
July 1993 Volume 3 Issue 1

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Article

IMMUNE REGULATION WITHIN HUMAN TUMORS - CONTRIBUTION OF DIFFERENT COMPONENTS OF THE TUMOR MICROENVIRONMENT

  • Authors:
    • J XIE
    • G GALLAGHER
  • View Affiliations / Copyright

    Affiliations: UNIV GLASGOW,GLASGOW ROYAL INFIRM,DEPT SURG,QUEEN ELIZABETH BLDG,GLASGOW G31 2ER,SCOTLAND.
  • Pages: 121-125
    |
    Published online on: July 1, 1993
       https://doi.org/10.3892/ijo.3.1.121
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Abstract

We have examined the ability of various components of breast, colorectal and ovarian tumours to regulate the activation and function of LAK cells and TILs, immune effectors which have been used as anti-tumour therapies. Tumour cell or supernatants derived from their short-term in vitro culture, inhibited the activation of PBMC by IL-2 but supported the continued proliferation of LAK or TIL cells which had already been activated. Despite being able to enhance or suppress growth of a range of cell lines, a cell-free, soluble preparation (TDS) from primary tumours was uniformly inhibitory to IL-2 activated cells, suggesting that it reflected the immunoregulatory nature of human tumours more accurately than cell-cultures or their supernatants.

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Copy and paste a formatted citation
Spandidos Publications style
XIE J and GALLAGHER G: IMMUNE REGULATION WITHIN HUMAN TUMORS - CONTRIBUTION OF DIFFERENT COMPONENTS OF THE TUMOR MICROENVIRONMENT. Int J Oncol 3: 121-125, 1993.
APA
XIE, J., & GALLAGHER, G. (1993). IMMUNE REGULATION WITHIN HUMAN TUMORS - CONTRIBUTION OF DIFFERENT COMPONENTS OF THE TUMOR MICROENVIRONMENT. International Journal of Oncology, 3, 121-125. https://doi.org/10.3892/ijo.3.1.121
MLA
XIE, J., GALLAGHER, G."IMMUNE REGULATION WITHIN HUMAN TUMORS - CONTRIBUTION OF DIFFERENT COMPONENTS OF THE TUMOR MICROENVIRONMENT". International Journal of Oncology 3.1 (1993): 121-125.
Chicago
XIE, J., GALLAGHER, G."IMMUNE REGULATION WITHIN HUMAN TUMORS - CONTRIBUTION OF DIFFERENT COMPONENTS OF THE TUMOR MICROENVIRONMENT". International Journal of Oncology 3, no. 1 (1993): 121-125. https://doi.org/10.3892/ijo.3.1.121
Copy and paste a formatted citation
x
Spandidos Publications style
XIE J and GALLAGHER G: IMMUNE REGULATION WITHIN HUMAN TUMORS - CONTRIBUTION OF DIFFERENT COMPONENTS OF THE TUMOR MICROENVIRONMENT. Int J Oncol 3: 121-125, 1993.
APA
XIE, J., & GALLAGHER, G. (1993). IMMUNE REGULATION WITHIN HUMAN TUMORS - CONTRIBUTION OF DIFFERENT COMPONENTS OF THE TUMOR MICROENVIRONMENT. International Journal of Oncology, 3, 121-125. https://doi.org/10.3892/ijo.3.1.121
MLA
XIE, J., GALLAGHER, G."IMMUNE REGULATION WITHIN HUMAN TUMORS - CONTRIBUTION OF DIFFERENT COMPONENTS OF THE TUMOR MICROENVIRONMENT". International Journal of Oncology 3.1 (1993): 121-125.
Chicago
XIE, J., GALLAGHER, G."IMMUNE REGULATION WITHIN HUMAN TUMORS - CONTRIBUTION OF DIFFERENT COMPONENTS OF THE TUMOR MICROENVIRONMENT". International Journal of Oncology 3, no. 1 (1993): 121-125. https://doi.org/10.3892/ijo.3.1.121
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