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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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August 1993 Volume 3 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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August 1993 Volume 3 Issue 2

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Article

RETINOIC ACID INDUCES LOSS OF VIRAL-DNA, PHENOTYPIC REVERSION AND TRANSFORMATION-RESISTANCE OF BOVINE PAPILLOMAVIRUS TYPE-1 DNA-TRANSFORMED CELLS

  • Authors:
    • G LI
    • SS TSANG
    • P LAM
    • HF STICH

  • View Affiliations / Copyright

    Affiliations: BRITISH COLUMBIA CANC RES CTR,ENVIRONM CARCINOGENESIS SECT,601 W 10TH AVE,VANCOUVER V5Z 1L3,BC,CANADA.
  • Pages: 319-324
    |
    Published online on: August 1, 1993
       https://doi.org/10.3892/ijo.3.2.319
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Abstract

Two revertant cell lines were obtained by treatment of bovine papillomavirus type 1 (BPV-1) DNA-transformed cell lines B3 and BF3 with 5 muM of all-trans-retinoic acid (RA) for 10 weeks. The revertant cells were devoid of detectable viral DNA, no longer exhibited a transformed morphology and lost the ability to form multilayered transformed foci. They replicated with a population doubling time of 16-18 hours, which was also characteristic of the C127, B3 and BF3 cells. They attained a similar saturation density as the C127 cells. However, the revertant cells were at least 5- to 7-fold more resistant than the parental C127 cells to neoplastic transformation induced by BPV-1 DNA.

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Copy and paste a formatted citation
Spandidos Publications style
LI G, TSANG S, LAM P and STICH H: RETINOIC ACID INDUCES LOSS OF VIRAL-DNA, PHENOTYPIC REVERSION AND TRANSFORMATION-RESISTANCE OF BOVINE PAPILLOMAVIRUS TYPE-1 DNA-TRANSFORMED CELLS. Int J Oncol 3: 319-324, 1993.
APA
LI, G., TSANG, S., LAM, P., & STICH, H. (1993). RETINOIC ACID INDUCES LOSS OF VIRAL-DNA, PHENOTYPIC REVERSION AND TRANSFORMATION-RESISTANCE OF BOVINE PAPILLOMAVIRUS TYPE-1 DNA-TRANSFORMED CELLS. International Journal of Oncology, 3, 319-324. https://doi.org/10.3892/ijo.3.2.319
MLA
LI, G., TSANG, S., LAM, P., STICH, H."RETINOIC ACID INDUCES LOSS OF VIRAL-DNA, PHENOTYPIC REVERSION AND TRANSFORMATION-RESISTANCE OF BOVINE PAPILLOMAVIRUS TYPE-1 DNA-TRANSFORMED CELLS". International Journal of Oncology 3.2 (1993): 319-324.
Chicago
LI, G., TSANG, S., LAM, P., STICH, H."RETINOIC ACID INDUCES LOSS OF VIRAL-DNA, PHENOTYPIC REVERSION AND TRANSFORMATION-RESISTANCE OF BOVINE PAPILLOMAVIRUS TYPE-1 DNA-TRANSFORMED CELLS". International Journal of Oncology 3, no. 2 (1993): 319-324. https://doi.org/10.3892/ijo.3.2.319
Copy and paste a formatted citation
x
Spandidos Publications style
LI G, TSANG S, LAM P and STICH H: RETINOIC ACID INDUCES LOSS OF VIRAL-DNA, PHENOTYPIC REVERSION AND TRANSFORMATION-RESISTANCE OF BOVINE PAPILLOMAVIRUS TYPE-1 DNA-TRANSFORMED CELLS. Int J Oncol 3: 319-324, 1993.
APA
LI, G., TSANG, S., LAM, P., & STICH, H. (1993). RETINOIC ACID INDUCES LOSS OF VIRAL-DNA, PHENOTYPIC REVERSION AND TRANSFORMATION-RESISTANCE OF BOVINE PAPILLOMAVIRUS TYPE-1 DNA-TRANSFORMED CELLS. International Journal of Oncology, 3, 319-324. https://doi.org/10.3892/ijo.3.2.319
MLA
LI, G., TSANG, S., LAM, P., STICH, H."RETINOIC ACID INDUCES LOSS OF VIRAL-DNA, PHENOTYPIC REVERSION AND TRANSFORMATION-RESISTANCE OF BOVINE PAPILLOMAVIRUS TYPE-1 DNA-TRANSFORMED CELLS". International Journal of Oncology 3.2 (1993): 319-324.
Chicago
LI, G., TSANG, S., LAM, P., STICH, H."RETINOIC ACID INDUCES LOSS OF VIRAL-DNA, PHENOTYPIC REVERSION AND TRANSFORMATION-RESISTANCE OF BOVINE PAPILLOMAVIRUS TYPE-1 DNA-TRANSFORMED CELLS". International Journal of Oncology 3, no. 2 (1993): 319-324. https://doi.org/10.3892/ijo.3.2.319
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