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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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October 1993 Volume 3 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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October 1993 Volume 3 Issue 4

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Article

IDENTIFICATION OF DNA BENDING REGION IN HUMAN C-MYC GENE

  • Authors:
    • Y NISHITA
    • H ARIGA
    • SMM IGUCHIARIGA
  • View Affiliations / Copyright

    Affiliations: HOKKAIDO UNIV,FAC PHARMACEUT SCI,KITA 12,NISHI 6,KITA KU,SAPPORO,HOKKAIDO 060,JAPAN. HOKKAIDO UNIV,COLL MED TECHNOL,KITA KU,SAPPORO,HOKKAIDO 060,JAPAN.
  • Pages: 701-706
    |
    Published online on: October 1, 1993
       https://doi.org/10.3892/ijo.3.4.701
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Abstract

DNA bending is considered to be important in DNA replication, transcription, and recombination. Several DNA bending regions reported so far are placed relatively near an origin of DNA replication or transcriptional regulatory regions. We have identified a DNA bending region in the human c-myc gene; it is located in the third exon, about 80 bases downstream of the coding region. This region includes a polyA addition signal. Deletion analysis of DNA showed that the sequence necessary for bending was about 130 base pairs long and possessed ten sets of adenine/thymine (AT) clusters. The bending region is specifically bound by proteins in HeLa cell nuclear extracts; the proteins seem to have a specific affinity for bent structures.

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Copy and paste a formatted citation
Spandidos Publications style
NISHITA Y, ARIGA H and IGUCHIARIGA S: IDENTIFICATION OF DNA BENDING REGION IN HUMAN C-MYC GENE. Int J Oncol 3: 701-706, 1993.
APA
NISHITA, Y., ARIGA, H., & IGUCHIARIGA, S. (1993). IDENTIFICATION OF DNA BENDING REGION IN HUMAN C-MYC GENE. International Journal of Oncology, 3, 701-706. https://doi.org/10.3892/ijo.3.4.701
MLA
NISHITA, Y., ARIGA, H., IGUCHIARIGA, S."IDENTIFICATION OF DNA BENDING REGION IN HUMAN C-MYC GENE". International Journal of Oncology 3.4 (1993): 701-706.
Chicago
NISHITA, Y., ARIGA, H., IGUCHIARIGA, S."IDENTIFICATION OF DNA BENDING REGION IN HUMAN C-MYC GENE". International Journal of Oncology 3, no. 4 (1993): 701-706. https://doi.org/10.3892/ijo.3.4.701
Copy and paste a formatted citation
x
Spandidos Publications style
NISHITA Y, ARIGA H and IGUCHIARIGA S: IDENTIFICATION OF DNA BENDING REGION IN HUMAN C-MYC GENE. Int J Oncol 3: 701-706, 1993.
APA
NISHITA, Y., ARIGA, H., & IGUCHIARIGA, S. (1993). IDENTIFICATION OF DNA BENDING REGION IN HUMAN C-MYC GENE. International Journal of Oncology, 3, 701-706. https://doi.org/10.3892/ijo.3.4.701
MLA
NISHITA, Y., ARIGA, H., IGUCHIARIGA, S."IDENTIFICATION OF DNA BENDING REGION IN HUMAN C-MYC GENE". International Journal of Oncology 3.4 (1993): 701-706.
Chicago
NISHITA, Y., ARIGA, H., IGUCHIARIGA, S."IDENTIFICATION OF DNA BENDING REGION IN HUMAN C-MYC GENE". International Journal of Oncology 3, no. 4 (1993): 701-706. https://doi.org/10.3892/ijo.3.4.701
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