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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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October 1993 Volume 3 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
October 1993 Volume 3 Issue 4

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Article

THE LACK OF IMPACT OF TREATMENT TIME ON THE OUTCOME OF DEFINITIVE RADIOTHERAPY FOR CARCINOMA OF THE PROSTATE

  • Authors:
    • MS ANSCHER
    • GS MONTANA
    • R DODGE
    • EF GAYDICA
    • MW DEWHIRST
    • LR PROSNITZ

  • View Affiliations / Copyright

    Affiliations: DUKE UNIV,MED CTR,DEPT COMMUNITY & FAMILY MED,DIV BIOMETRY & MED INFORMAT,DURHAM,NC 27710. MOORE REG HOSP,DEPT RADIAT ONCOL,PINEHURST,NC.
  • Pages: 707-711
    |
    Published online on: October 1, 1993
       https://doi.org/10.3892/ijo.3.4.707
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Abstract

The records of 180 patients definitively irradiated for newly diagnosed adenocarcinoma of the prostate between 1970 and 1988 at Duke University Medical Center (107 patients from 1970-1983) and Moore Regional Hospital (73 patients from 1981-1988) were reviewed to determine the impact of overall treatment time on survival, local control, disease-free survival, and time to distant metastases. Using multivariate analysis we controlled for the influence of the following prognostic variables in addition to overall treatment time: age, clinical stage, histologic grade, acid phosphatase, type of biopsy, radiation dose, and use of hormonal therapy. Median follow-up was 46 months. Eighty-three percent of patients had clinical Stage B or C tumors. This is the first study to consider how treatment time might interact with recognized prognostic variables to influence treatment outcomes in prostate cancer and we found that overall treatment time did not significantly influence any of the outcome endpoints. Future research designed to improve local control after radiotherapy for prostate cancer should not focus on altering treatment time, but should explore other avenues such as hyperthermia, chemical modifiers or conformal therapy.

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Copy and paste a formatted citation
Spandidos Publications style
ANSCHER M, MONTANA G, DODGE R, GAYDICA E, DEWHIRST M and PROSNITZ L: THE LACK OF IMPACT OF TREATMENT TIME ON THE OUTCOME OF DEFINITIVE RADIOTHERAPY FOR CARCINOMA OF THE PROSTATE. Int J Oncol 3: 707-711, 1993.
APA
ANSCHER, M., MONTANA, G., DODGE, R., GAYDICA, E., DEWHIRST, M., & PROSNITZ, L. (1993). THE LACK OF IMPACT OF TREATMENT TIME ON THE OUTCOME OF DEFINITIVE RADIOTHERAPY FOR CARCINOMA OF THE PROSTATE. International Journal of Oncology, 3, 707-711. https://doi.org/10.3892/ijo.3.4.707
MLA
ANSCHER, M., MONTANA, G., DODGE, R., GAYDICA, E., DEWHIRST, M., PROSNITZ, L."THE LACK OF IMPACT OF TREATMENT TIME ON THE OUTCOME OF DEFINITIVE RADIOTHERAPY FOR CARCINOMA OF THE PROSTATE". International Journal of Oncology 3.4 (1993): 707-711.
Chicago
ANSCHER, M., MONTANA, G., DODGE, R., GAYDICA, E., DEWHIRST, M., PROSNITZ, L."THE LACK OF IMPACT OF TREATMENT TIME ON THE OUTCOME OF DEFINITIVE RADIOTHERAPY FOR CARCINOMA OF THE PROSTATE". International Journal of Oncology 3, no. 4 (1993): 707-711. https://doi.org/10.3892/ijo.3.4.707
Copy and paste a formatted citation
x
Spandidos Publications style
ANSCHER M, MONTANA G, DODGE R, GAYDICA E, DEWHIRST M and PROSNITZ L: THE LACK OF IMPACT OF TREATMENT TIME ON THE OUTCOME OF DEFINITIVE RADIOTHERAPY FOR CARCINOMA OF THE PROSTATE. Int J Oncol 3: 707-711, 1993.
APA
ANSCHER, M., MONTANA, G., DODGE, R., GAYDICA, E., DEWHIRST, M., & PROSNITZ, L. (1993). THE LACK OF IMPACT OF TREATMENT TIME ON THE OUTCOME OF DEFINITIVE RADIOTHERAPY FOR CARCINOMA OF THE PROSTATE. International Journal of Oncology, 3, 707-711. https://doi.org/10.3892/ijo.3.4.707
MLA
ANSCHER, M., MONTANA, G., DODGE, R., GAYDICA, E., DEWHIRST, M., PROSNITZ, L."THE LACK OF IMPACT OF TREATMENT TIME ON THE OUTCOME OF DEFINITIVE RADIOTHERAPY FOR CARCINOMA OF THE PROSTATE". International Journal of Oncology 3.4 (1993): 707-711.
Chicago
ANSCHER, M., MONTANA, G., DODGE, R., GAYDICA, E., DEWHIRST, M., PROSNITZ, L."THE LACK OF IMPACT OF TREATMENT TIME ON THE OUTCOME OF DEFINITIVE RADIOTHERAPY FOR CARCINOMA OF THE PROSTATE". International Journal of Oncology 3, no. 4 (1993): 707-711. https://doi.org/10.3892/ijo.3.4.707
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