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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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July 2007 Volume 31 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July 2007 Volume 31 Issue 1

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Review

Molecular approaches to the staging of head and neck carcinomas (Review)

  • Authors:
    • Daniela Gasparotto
    • Roberta Maestro

  • View Affiliations / Copyright

    Affiliations: Experimental Oncology 1, CRO-IRCCS, Aviano National Cancer Institute, I-33081 Aviano (PN), Italy
  • Pages: 175-180
    |
    Published online on: July 1, 2007
       https://doi.org/10.3892/ijo.31.1.175
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Abstract

Despite the efforts during the last decades to improve clinical management and therapy, carcinomas of the head and neck still represent a disease with an unfavourable course. Over 50% of the patients die from their disease within 5 years after diagnosis, with tumour recurrence, metastasis, and development of second primary neoplasms as major causes of treatment failure. In addition, surgical treatment of locally advanced disease often results in invalidating and disfiguring conditions that heavily affect patients' quality of life. Current criteria of tumour staging, essentially based on clinical and pathological assessment, fail to prove effective in providing reliable information on tumour prognosis or supporting an optimized planning of the therapies, prompting the identification of new and more accurate staging criteria. This review focuses on the impact of molecular biology in HNSCC staging, namely differentiation of second primary lesions from recurrence/metastasis and detection of lymph node micrometastasis, and highlights how the integration of the histopathological diagnosis with molecular analyses may result in a better management of HNSCC patients.

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Copy and paste a formatted citation
Spandidos Publications style
Gasparotto D and Maestro R: Molecular approaches to the staging of head and neck carcinomas (Review). Int J Oncol 31: 175-180, 2007.
APA
Gasparotto, D., & Maestro, R. (2007). Molecular approaches to the staging of head and neck carcinomas (Review). International Journal of Oncology, 31, 175-180. https://doi.org/10.3892/ijo.31.1.175
MLA
Gasparotto, D., Maestro, R."Molecular approaches to the staging of head and neck carcinomas (Review)". International Journal of Oncology 31.1 (2007): 175-180.
Chicago
Gasparotto, D., Maestro, R."Molecular approaches to the staging of head and neck carcinomas (Review)". International Journal of Oncology 31, no. 1 (2007): 175-180. https://doi.org/10.3892/ijo.31.1.175
Copy and paste a formatted citation
x
Spandidos Publications style
Gasparotto D and Maestro R: Molecular approaches to the staging of head and neck carcinomas (Review). Int J Oncol 31: 175-180, 2007.
APA
Gasparotto, D., & Maestro, R. (2007). Molecular approaches to the staging of head and neck carcinomas (Review). International Journal of Oncology, 31, 175-180. https://doi.org/10.3892/ijo.31.1.175
MLA
Gasparotto, D., Maestro, R."Molecular approaches to the staging of head and neck carcinomas (Review)". International Journal of Oncology 31.1 (2007): 175-180.
Chicago
Gasparotto, D., Maestro, R."Molecular approaches to the staging of head and neck carcinomas (Review)". International Journal of Oncology 31, no. 1 (2007): 175-180. https://doi.org/10.3892/ijo.31.1.175
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