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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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February 1994 Volume 4 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
February 1994 Volume 4 Issue 2

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Review

THE RECEPTOR FOR EGF AND ITS LIGANDS - EXPRESSION, PROGNOSTIC VALUE AND TARGET FOR THERAPY IN CANCER (REVIEW)

  • Authors:
    • H MODJTAHEDI
    • C DEAN

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    Affiliations: Affliations not specified
  • Pages: 277-296
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    Published online on: February 1, 1994
       https://doi.org/10.3892/ijo.4.2.277
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Abstract

The results of recent studies suggest that overexpression of the EGF receptor accompanied by production of its ligands is an important characteristic of human squamous cell carcinomas. The EGF receptor which transmits the growth promoting or inhibitory effects of epidermal growth factor (EGF), transforming growth factor alpha (TGFalpha) and amphiregulin is a member of the type I family of growth factor receptors which possess tyrosine kinase activity. In this review we a) discuss the role played by this receptor and its ligands in the transformation of normal cells, b) analyze the evidence for expression of the receptor and its ligands as prognostic markers in cancer patients and c) indicate ways that the overexpressed EGF-receptor system on human malignant cells can be targeted for therapeutic application.

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Copy and paste a formatted citation
Spandidos Publications style
MODJTAHEDI H and DEAN C: THE RECEPTOR FOR EGF AND ITS LIGANDS - EXPRESSION, PROGNOSTIC VALUE AND TARGET FOR THERAPY IN CANCER (REVIEW). Int J Oncol 4: 277-296, 1994.
APA
MODJTAHEDI, H., & DEAN, C. (1994). THE RECEPTOR FOR EGF AND ITS LIGANDS - EXPRESSION, PROGNOSTIC VALUE AND TARGET FOR THERAPY IN CANCER (REVIEW). International Journal of Oncology, 4, 277-296. https://doi.org/10.3892/ijo.4.2.277
MLA
MODJTAHEDI, H., DEAN, C."THE RECEPTOR FOR EGF AND ITS LIGANDS - EXPRESSION, PROGNOSTIC VALUE AND TARGET FOR THERAPY IN CANCER (REVIEW)". International Journal of Oncology 4.2 (1994): 277-296.
Chicago
MODJTAHEDI, H., DEAN, C."THE RECEPTOR FOR EGF AND ITS LIGANDS - EXPRESSION, PROGNOSTIC VALUE AND TARGET FOR THERAPY IN CANCER (REVIEW)". International Journal of Oncology 4, no. 2 (1994): 277-296. https://doi.org/10.3892/ijo.4.2.277
Copy and paste a formatted citation
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Spandidos Publications style
MODJTAHEDI H and DEAN C: THE RECEPTOR FOR EGF AND ITS LIGANDS - EXPRESSION, PROGNOSTIC VALUE AND TARGET FOR THERAPY IN CANCER (REVIEW). Int J Oncol 4: 277-296, 1994.
APA
MODJTAHEDI, H., & DEAN, C. (1994). THE RECEPTOR FOR EGF AND ITS LIGANDS - EXPRESSION, PROGNOSTIC VALUE AND TARGET FOR THERAPY IN CANCER (REVIEW). International Journal of Oncology, 4, 277-296. https://doi.org/10.3892/ijo.4.2.277
MLA
MODJTAHEDI, H., DEAN, C."THE RECEPTOR FOR EGF AND ITS LIGANDS - EXPRESSION, PROGNOSTIC VALUE AND TARGET FOR THERAPY IN CANCER (REVIEW)". International Journal of Oncology 4.2 (1994): 277-296.
Chicago
MODJTAHEDI, H., DEAN, C."THE RECEPTOR FOR EGF AND ITS LIGANDS - EXPRESSION, PROGNOSTIC VALUE AND TARGET FOR THERAPY IN CANCER (REVIEW)". International Journal of Oncology 4, no. 2 (1994): 277-296. https://doi.org/10.3892/ijo.4.2.277
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