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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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April 1994 Volume 4 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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April 1994 Volume 4 Issue 4

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Article

INCREASES OF STROMELYSIN MESSENGER-RNA EXPRESSION IN RAS-TRANSFORMED REF CELLS IN-VIVO

  • Authors:
    • G ENGEL
    • P POPOWICZ
    • S LINDER

  • View Affiliations / Copyright

    Affiliations: KAROLINSKA INST,RADIUMHEMMET,DEPT GEN ONCOL,DIV EXPTL,S-17176 STOCKHOLM,SWEDEN. KAROLINSKA HOSP,S-17176 STOCKHOLM,SWEDEN.
  • Pages: 891-896
    |
    Published online on: April 1, 1994
       https://doi.org/10.3892/ijo.4.4.891
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Abstract

Interstitial collagenase and stromelysin mRNA expression was examined in six rat cell lines isolated after transfection of embryo fibroblasts with polyomavirus large-T and T24-ras oncogenes. Increased levels of stromelysin mRNA were observed in tumors formed by cells with low levels of stromelysin expression before injection, whereas interstitial collagenase mRNA levels were not elevated in tumors. The lung colonizing - but not the chemoinvasive capacity - of two of these cell lines increased following growth in vivo. The increase in stromelysin expression in tumors was not necessarily paralleled by an increase in ras expression. These findings may be relevant to the phenomenon of clonal dominance of metastatic cells in primary tumors.

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Copy and paste a formatted citation
Spandidos Publications style
ENGEL G, POPOWICZ P and LINDER S: INCREASES OF STROMELYSIN MESSENGER-RNA EXPRESSION IN RAS-TRANSFORMED REF CELLS IN-VIVO. Int J Oncol 4: 891-896, 1994.
APA
ENGEL, G., POPOWICZ, P., & LINDER, S. (1994). INCREASES OF STROMELYSIN MESSENGER-RNA EXPRESSION IN RAS-TRANSFORMED REF CELLS IN-VIVO. International Journal of Oncology, 4, 891-896. https://doi.org/10.3892/ijo.4.4.891
MLA
ENGEL, G., POPOWICZ, P., LINDER, S."INCREASES OF STROMELYSIN MESSENGER-RNA EXPRESSION IN RAS-TRANSFORMED REF CELLS IN-VIVO". International Journal of Oncology 4.4 (1994): 891-896.
Chicago
ENGEL, G., POPOWICZ, P., LINDER, S."INCREASES OF STROMELYSIN MESSENGER-RNA EXPRESSION IN RAS-TRANSFORMED REF CELLS IN-VIVO". International Journal of Oncology 4, no. 4 (1994): 891-896. https://doi.org/10.3892/ijo.4.4.891
Copy and paste a formatted citation
x
Spandidos Publications style
ENGEL G, POPOWICZ P and LINDER S: INCREASES OF STROMELYSIN MESSENGER-RNA EXPRESSION IN RAS-TRANSFORMED REF CELLS IN-VIVO. Int J Oncol 4: 891-896, 1994.
APA
ENGEL, G., POPOWICZ, P., & LINDER, S. (1994). INCREASES OF STROMELYSIN MESSENGER-RNA EXPRESSION IN RAS-TRANSFORMED REF CELLS IN-VIVO. International Journal of Oncology, 4, 891-896. https://doi.org/10.3892/ijo.4.4.891
MLA
ENGEL, G., POPOWICZ, P., LINDER, S."INCREASES OF STROMELYSIN MESSENGER-RNA EXPRESSION IN RAS-TRANSFORMED REF CELLS IN-VIVO". International Journal of Oncology 4.4 (1994): 891-896.
Chicago
ENGEL, G., POPOWICZ, P., LINDER, S."INCREASES OF STROMELYSIN MESSENGER-RNA EXPRESSION IN RAS-TRANSFORMED REF CELLS IN-VIVO". International Journal of Oncology 4, no. 4 (1994): 891-896. https://doi.org/10.3892/ijo.4.4.891
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