GENETIC STABILITY OF MICROSATELLITES IN HUMAN NEUROBLASTOMAS

  • Authors:
    • M GEHRING
    • F BERTHOLD
    • M SCHWAB
    • L AMLER
  • View Affiliations

  • Published online on: May 1, 1994     https://doi.org/10.3892/ijo.4.5.1043
  • Pages: 1043-1045
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Abstract

Genetic instability resulting from deficiency in replication error repair (RER) has been detected in a variety of human cancers. We have examined the stability of five 1p microsatellites in 51 human neuroblastomas including stages 1, 2, 3, 4 and 4s. None of the tumors showed an aberrant pattern indicating RER at any microsatellite. Our results do not support a major role for increased genetic instability as the result of deficient replication error repair in neuroblastoma.

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May 1994
Volume 4 Issue 5

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
GEHRING M, BERTHOLD F, SCHWAB M and AMLER L: GENETIC STABILITY OF MICROSATELLITES IN HUMAN NEUROBLASTOMAS. Int J Oncol 4: 1043-1045, 1994
APA
GEHRING, M., BERTHOLD, F., SCHWAB, M., & AMLER, L. (1994). GENETIC STABILITY OF MICROSATELLITES IN HUMAN NEUROBLASTOMAS. International Journal of Oncology, 4, 1043-1045. https://doi.org/10.3892/ijo.4.5.1043
MLA
GEHRING, M., BERTHOLD, F., SCHWAB, M., AMLER, L."GENETIC STABILITY OF MICROSATELLITES IN HUMAN NEUROBLASTOMAS". International Journal of Oncology 4.5 (1994): 1043-1045.
Chicago
GEHRING, M., BERTHOLD, F., SCHWAB, M., AMLER, L."GENETIC STABILITY OF MICROSATELLITES IN HUMAN NEUROBLASTOMAS". International Journal of Oncology 4, no. 5 (1994): 1043-1045. https://doi.org/10.3892/ijo.4.5.1043