EXPRESSION OF SEX-HORMONE RECEPTORS AND CLINICOPATHOLOGICAL FINDINGS IN HEPATOCELLULAR-CARCINOMA

  • Authors:
    • H ISHIZU
    • Y UNE
    • H GONDO
    • H KAMEDA
    • J UCHINO
  • View Affiliations

  • Published online on: June 1, 1994     https://doi.org/10.3892/ijo.4.6.1349
  • Pages: 1349-1352
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Abstract

We studied the expresssion of estrogen (ER), progesterone (PgR), and androgen receptors (AR) in hepatocellular carcinoma (HCC) and found expression in (7/36), 3.2% (1/31), 16.7% (4/24) of cases, respectively. The expression of ER did not correlate with histological grade, tumor size, or stage of disease. On the other hand, all the patients with AR-positive tumors had stage IV disease, and only 25% of the patients with AR-negative tumors had stage IV disease. The survival was not influenced by the expression pattern of ER, however, the survival of the patients with AR-positive tumors tended to be worse than that of patients with AR-negative tumors. We suggest that the AR expression correlates better with poor outcome in HCC than the ER expression.

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June 1994
Volume 4 Issue 6

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
ISHIZU H, UNE Y, GONDO H, KAMEDA H and UCHINO J: EXPRESSION OF SEX-HORMONE RECEPTORS AND CLINICOPATHOLOGICAL FINDINGS IN HEPATOCELLULAR-CARCINOMA. Int J Oncol 4: 1349-1352, 1994
APA
ISHIZU, H., UNE, Y., GONDO, H., KAMEDA, H., & UCHINO, J. (1994). EXPRESSION OF SEX-HORMONE RECEPTORS AND CLINICOPATHOLOGICAL FINDINGS IN HEPATOCELLULAR-CARCINOMA. International Journal of Oncology, 4, 1349-1352. https://doi.org/10.3892/ijo.4.6.1349
MLA
ISHIZU, H., UNE, Y., GONDO, H., KAMEDA, H., UCHINO, J."EXPRESSION OF SEX-HORMONE RECEPTORS AND CLINICOPATHOLOGICAL FINDINGS IN HEPATOCELLULAR-CARCINOMA". International Journal of Oncology 4.6 (1994): 1349-1352.
Chicago
ISHIZU, H., UNE, Y., GONDO, H., KAMEDA, H., UCHINO, J."EXPRESSION OF SEX-HORMONE RECEPTORS AND CLINICOPATHOLOGICAL FINDINGS IN HEPATOCELLULAR-CARCINOMA". International Journal of Oncology 4, no. 6 (1994): 1349-1352. https://doi.org/10.3892/ijo.4.6.1349