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S-100 PROTEIN-POSITIVE DENDRITIC CELLS DETECTED IN HEPATOCELLULAR-CARCINOMA IN RELATION TO TUMOR PROGRESSION AND PROGNOSIS

  • Authors:
    • E IDO
    • M FURIHATA
    • Y OHTSUKI
    • J IWATA
    • H SONOBE

  • View Affiliations

  • Published online on: August 1, 1994     https://doi.org/10.3892/ijo.5.2.231
  • Pages: 231-236
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
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Abstract

The presence of S-100 protein positive dendritic cells (S-100(+)DC) in primary hepatocellular carcinoma (HCC) were immunohistochemically investigated in relation to clinicopathological factors. The patients who showed a marked infiltration of S-100(+)DC survived longer especially in the group of non-curative resection (P<0.05). In addition, the density numbers of S-100(+)DC related well with the rate of growth of each tumor nodule calculated by ultrasonography (r=0.575, P<0.01). These results indicate that, S-100(+) DC, acting as antigen presenting cells, may play an important role in the host's immune reaction against HCC and are a useful marker for tumor growth and prognosis in HCC.

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August 1994
Volume 5 Issue 2

Print ISSN: 1019-6439
Online ISSN:1791-2423

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  • CiteScore: 11.4
  • CiteScore Rank: Q1: #40/366 Oncology
  • Source Normalized Impact per Paper (SNIP): 1.125
  • SCImago Journal Rank (SJR): 1.105
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Spandidos Publications style
IDO E, FURIHATA M, OHTSUKI Y, IWATA J and SONOBE H: S-100 PROTEIN-POSITIVE DENDRITIC CELLS DETECTED IN HEPATOCELLULAR-CARCINOMA IN RELATION TO TUMOR PROGRESSION AND PROGNOSIS. Int J Oncol 5: 231-236, 1994
APA
IDO, E., FURIHATA, M., OHTSUKI, Y., IWATA, J., & SONOBE, H. (1994). S-100 PROTEIN-POSITIVE DENDRITIC CELLS DETECTED IN HEPATOCELLULAR-CARCINOMA IN RELATION TO TUMOR PROGRESSION AND PROGNOSIS. International Journal of Oncology, 5, 231-236. https://doi.org/10.3892/ijo.5.2.231
MLA
IDO, E., FURIHATA, M., OHTSUKI, Y., IWATA, J., SONOBE, H."S-100 PROTEIN-POSITIVE DENDRITIC CELLS DETECTED IN HEPATOCELLULAR-CARCINOMA IN RELATION TO TUMOR PROGRESSION AND PROGNOSIS". International Journal of Oncology 5.2 (1994): 231-236.
Chicago
IDO, E., FURIHATA, M., OHTSUKI, Y., IWATA, J., SONOBE, H."S-100 PROTEIN-POSITIVE DENDRITIC CELLS DETECTED IN HEPATOCELLULAR-CARCINOMA IN RELATION TO TUMOR PROGRESSION AND PROGNOSIS". International Journal of Oncology 5, no. 2 (1994): 231-236. https://doi.org/10.3892/ijo.5.2.231