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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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October 1994 Volume 5 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
October 1994 Volume 5 Issue 4

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Article

TUMOR VASCULAR SHUTDOWN FOLLOWING PHOTODYNAMIC THERAPY BASED ON POLYHEMATOPORPHYRIN OR 5-AMINOLEVULINIC ACID

  • Authors:
    • DJH ROBERTS
    • F CAIRNDUFF
    • I DRIVER
    • B DIXON
    • SB BROWN

  • View Affiliations / Copyright

    Affiliations: COOKRIDGE HOSP,DEPT CLIN ONCOL,LEEDS LS16 6QB,W YORKSHIRE,ENGLAND. COOKRIDGE HOSP,DEPT MED PHYS,LEEDS LS16 6QB,W YORKSHIRE,ENGLAND. UNIV LEEDS,DEPT BIOCHEM & MOLEC BIOL,LEEDS LS2 9JT,W YORKSHIRE,ENGLAND.
  • Pages: 763-768
    |
    Published online on: October 1, 1994
       https://doi.org/10.3892/ijo.5.4.763
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Abstract

The effects of photodynamic therapy (PDT) based on polyhaematoporphyrin (PHP) or 5-aminolaevulinic acid (ALA) on the tumour vascular perfusion (TVP) of a rat fibrosarcoma were examined using an (RbCl)-Rb-86 extraction technique. Both forms of therapy induced large and highly significant reductions in TVP, countering the previous suggestion that ALA-PDT has no vascular effects. Ultrasensitive digital imaging fluorescence microscopy indicated that ALA-induced PpIX was distributed relatively evenly throughout the tumour. Use of Hoechst 33342 as a vascular marker revealed that PpIX was also present in cells lining the tumour microvascular spaces, contrary to previous findings.

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Copy and paste a formatted citation
Spandidos Publications style
ROBERTS D, CAIRNDUFF F, DRIVER I, DIXON B and BROWN S: TUMOR VASCULAR SHUTDOWN FOLLOWING PHOTODYNAMIC THERAPY BASED ON POLYHEMATOPORPHYRIN OR 5-AMINOLEVULINIC ACID. Int J Oncol 5: 763-768, 1994.
APA
ROBERTS, D., CAIRNDUFF, F., DRIVER, I., DIXON, B., & BROWN, S. (1994). TUMOR VASCULAR SHUTDOWN FOLLOWING PHOTODYNAMIC THERAPY BASED ON POLYHEMATOPORPHYRIN OR 5-AMINOLEVULINIC ACID. International Journal of Oncology, 5, 763-768. https://doi.org/10.3892/ijo.5.4.763
MLA
ROBERTS, D., CAIRNDUFF, F., DRIVER, I., DIXON, B., BROWN, S."TUMOR VASCULAR SHUTDOWN FOLLOWING PHOTODYNAMIC THERAPY BASED ON POLYHEMATOPORPHYRIN OR 5-AMINOLEVULINIC ACID". International Journal of Oncology 5.4 (1994): 763-768.
Chicago
ROBERTS, D., CAIRNDUFF, F., DRIVER, I., DIXON, B., BROWN, S."TUMOR VASCULAR SHUTDOWN FOLLOWING PHOTODYNAMIC THERAPY BASED ON POLYHEMATOPORPHYRIN OR 5-AMINOLEVULINIC ACID". International Journal of Oncology 5, no. 4 (1994): 763-768. https://doi.org/10.3892/ijo.5.4.763
Copy and paste a formatted citation
x
Spandidos Publications style
ROBERTS D, CAIRNDUFF F, DRIVER I, DIXON B and BROWN S: TUMOR VASCULAR SHUTDOWN FOLLOWING PHOTODYNAMIC THERAPY BASED ON POLYHEMATOPORPHYRIN OR 5-AMINOLEVULINIC ACID. Int J Oncol 5: 763-768, 1994.
APA
ROBERTS, D., CAIRNDUFF, F., DRIVER, I., DIXON, B., & BROWN, S. (1994). TUMOR VASCULAR SHUTDOWN FOLLOWING PHOTODYNAMIC THERAPY BASED ON POLYHEMATOPORPHYRIN OR 5-AMINOLEVULINIC ACID. International Journal of Oncology, 5, 763-768. https://doi.org/10.3892/ijo.5.4.763
MLA
ROBERTS, D., CAIRNDUFF, F., DRIVER, I., DIXON, B., BROWN, S."TUMOR VASCULAR SHUTDOWN FOLLOWING PHOTODYNAMIC THERAPY BASED ON POLYHEMATOPORPHYRIN OR 5-AMINOLEVULINIC ACID". International Journal of Oncology 5.4 (1994): 763-768.
Chicago
ROBERTS, D., CAIRNDUFF, F., DRIVER, I., DIXON, B., BROWN, S."TUMOR VASCULAR SHUTDOWN FOLLOWING PHOTODYNAMIC THERAPY BASED ON POLYHEMATOPORPHYRIN OR 5-AMINOLEVULINIC ACID". International Journal of Oncology 5, no. 4 (1994): 763-768. https://doi.org/10.3892/ijo.5.4.763
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