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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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December 1994 Volume 5 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
December 1994 Volume 5 Issue 6

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Article

EXPRESSION OF MATRIX METALLOPROTEINASE-2 (MMP-2) IN CERVICAL NEOPLASIA - IMMUNOHISTOCHEMICAL AND IN-SITU HYBRIDIZATION STUDIES

  • Authors:
    • S OTA
    • Y MIYAJIMA
    • A NAKASHIMA
    • M MORIMATSU
    • M YAKUSHIJI
  • View Affiliations / Copyright

    Affiliations: KURUME UNIV,SCH MED,DEPT GYNECOL & OBSTET,KURUME,FUKUOKA 830,JAPAN.
  • Pages: 1301-1304
    |
    Published online on: December 1, 1994
       https://doi.org/10.3892/ijo.5.6.1301
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Abstract

The expression of matrix metalloproteinase-2 (MMP-2, type IV collagenase, 72 kDa) in 47 cervical precancerous and cancerous lesions were localised by in situ hybridization and immunohistochemical studies. MMP-2 mRNA was present in the stromal cells surrounding invasive cells in the majority of squamous cell carcinomas and adenocarcinomas. In contrast, MMP-2 immunoreactivity was found in the epithelial cells. Our results indicate that there may be some interaction between carcinoma cells and stromal cells to produce MMP-2 which may contribute to the destruction of the extracellular matrix in invasive cervical carcinomas.

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Copy and paste a formatted citation
Spandidos Publications style
OTA S, MIYAJIMA Y, NAKASHIMA A, MORIMATSU M and YAKUSHIJI M: EXPRESSION OF MATRIX METALLOPROTEINASE-2 (MMP-2) IN CERVICAL NEOPLASIA - IMMUNOHISTOCHEMICAL AND IN-SITU HYBRIDIZATION STUDIES. Int J Oncol 5: 1301-1304, 1994.
APA
OTA, S., MIYAJIMA, Y., NAKASHIMA, A., MORIMATSU, M., & YAKUSHIJI, M. (1994). EXPRESSION OF MATRIX METALLOPROTEINASE-2 (MMP-2) IN CERVICAL NEOPLASIA - IMMUNOHISTOCHEMICAL AND IN-SITU HYBRIDIZATION STUDIES. International Journal of Oncology, 5, 1301-1304. https://doi.org/10.3892/ijo.5.6.1301
MLA
OTA, S., MIYAJIMA, Y., NAKASHIMA, A., MORIMATSU, M., YAKUSHIJI, M."EXPRESSION OF MATRIX METALLOPROTEINASE-2 (MMP-2) IN CERVICAL NEOPLASIA - IMMUNOHISTOCHEMICAL AND IN-SITU HYBRIDIZATION STUDIES". International Journal of Oncology 5.6 (1994): 1301-1304.
Chicago
OTA, S., MIYAJIMA, Y., NAKASHIMA, A., MORIMATSU, M., YAKUSHIJI, M."EXPRESSION OF MATRIX METALLOPROTEINASE-2 (MMP-2) IN CERVICAL NEOPLASIA - IMMUNOHISTOCHEMICAL AND IN-SITU HYBRIDIZATION STUDIES". International Journal of Oncology 5, no. 6 (1994): 1301-1304. https://doi.org/10.3892/ijo.5.6.1301
Copy and paste a formatted citation
x
Spandidos Publications style
OTA S, MIYAJIMA Y, NAKASHIMA A, MORIMATSU M and YAKUSHIJI M: EXPRESSION OF MATRIX METALLOPROTEINASE-2 (MMP-2) IN CERVICAL NEOPLASIA - IMMUNOHISTOCHEMICAL AND IN-SITU HYBRIDIZATION STUDIES. Int J Oncol 5: 1301-1304, 1994.
APA
OTA, S., MIYAJIMA, Y., NAKASHIMA, A., MORIMATSU, M., & YAKUSHIJI, M. (1994). EXPRESSION OF MATRIX METALLOPROTEINASE-2 (MMP-2) IN CERVICAL NEOPLASIA - IMMUNOHISTOCHEMICAL AND IN-SITU HYBRIDIZATION STUDIES. International Journal of Oncology, 5, 1301-1304. https://doi.org/10.3892/ijo.5.6.1301
MLA
OTA, S., MIYAJIMA, Y., NAKASHIMA, A., MORIMATSU, M., YAKUSHIJI, M."EXPRESSION OF MATRIX METALLOPROTEINASE-2 (MMP-2) IN CERVICAL NEOPLASIA - IMMUNOHISTOCHEMICAL AND IN-SITU HYBRIDIZATION STUDIES". International Journal of Oncology 5.6 (1994): 1301-1304.
Chicago
OTA, S., MIYAJIMA, Y., NAKASHIMA, A., MORIMATSU, M., YAKUSHIJI, M."EXPRESSION OF MATRIX METALLOPROTEINASE-2 (MMP-2) IN CERVICAL NEOPLASIA - IMMUNOHISTOCHEMICAL AND IN-SITU HYBRIDIZATION STUDIES". International Journal of Oncology 5, no. 6 (1994): 1301-1304. https://doi.org/10.3892/ijo.5.6.1301
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