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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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May 1995 Volume 6 Issue 5

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
May 1995 Volume 6 Issue 5

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Article

INFLUENCE OF CHEMOTHERAPEUTIC-AGENTS ON THE PROLIFERATION OF CAPILLARY ENDOTHELIAL-CELLS AND TUMOR ANGIOGENESIS IN MURINE BLADDER-CANCER

  • Authors:
    • KE LEE
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    Affiliations: Affliations not specified
  • Pages: 1021-1026
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    Published online on: May 1, 1995
       https://doi.org/10.3892/ijo.6.5.1021
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Abstract

The current studies investigated the potential of conventional chemotherapeutic agents to inhibit the proliferation of capillary endothelial cells and to affect tumor angiogenesis using a murine bladder cancer model. Endothelial cell lines were established from the skin and used for an in vitro target. The anti-angiogenesis activity was assessed by an i.d. assay. Among the eight agents examined, adriamycin, 4-hydroperoxycyclophosphamide, and methotrexate preferentially inhibited the cell proliferation. However, these agents showed no influence on tumor angiogenesis. In contrast, mitomycin C, which was less cytotoxic to endothelial cells in vitro, showed a significant anti-angiogenesis activity. The data suggest that certain chemotherapeutic agents had anti-angiogenesis activity distinct from cytotoxicity.

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Copy and paste a formatted citation
Spandidos Publications style
LEE K: INFLUENCE OF CHEMOTHERAPEUTIC-AGENTS ON THE PROLIFERATION OF CAPILLARY ENDOTHELIAL-CELLS AND TUMOR ANGIOGENESIS IN MURINE BLADDER-CANCER. Int J Oncol 6: 1021-1026, 1995.
APA
LEE, K. (1995). INFLUENCE OF CHEMOTHERAPEUTIC-AGENTS ON THE PROLIFERATION OF CAPILLARY ENDOTHELIAL-CELLS AND TUMOR ANGIOGENESIS IN MURINE BLADDER-CANCER. International Journal of Oncology, 6, 1021-1026. https://doi.org/10.3892/ijo.6.5.1021
MLA
LEE, K."INFLUENCE OF CHEMOTHERAPEUTIC-AGENTS ON THE PROLIFERATION OF CAPILLARY ENDOTHELIAL-CELLS AND TUMOR ANGIOGENESIS IN MURINE BLADDER-CANCER". International Journal of Oncology 6.5 (1995): 1021-1026.
Chicago
LEE, K."INFLUENCE OF CHEMOTHERAPEUTIC-AGENTS ON THE PROLIFERATION OF CAPILLARY ENDOTHELIAL-CELLS AND TUMOR ANGIOGENESIS IN MURINE BLADDER-CANCER". International Journal of Oncology 6, no. 5 (1995): 1021-1026. https://doi.org/10.3892/ijo.6.5.1021
Copy and paste a formatted citation
x
Spandidos Publications style
LEE K: INFLUENCE OF CHEMOTHERAPEUTIC-AGENTS ON THE PROLIFERATION OF CAPILLARY ENDOTHELIAL-CELLS AND TUMOR ANGIOGENESIS IN MURINE BLADDER-CANCER. Int J Oncol 6: 1021-1026, 1995.
APA
LEE, K. (1995). INFLUENCE OF CHEMOTHERAPEUTIC-AGENTS ON THE PROLIFERATION OF CAPILLARY ENDOTHELIAL-CELLS AND TUMOR ANGIOGENESIS IN MURINE BLADDER-CANCER. International Journal of Oncology, 6, 1021-1026. https://doi.org/10.3892/ijo.6.5.1021
MLA
LEE, K."INFLUENCE OF CHEMOTHERAPEUTIC-AGENTS ON THE PROLIFERATION OF CAPILLARY ENDOTHELIAL-CELLS AND TUMOR ANGIOGENESIS IN MURINE BLADDER-CANCER". International Journal of Oncology 6.5 (1995): 1021-1026.
Chicago
LEE, K."INFLUENCE OF CHEMOTHERAPEUTIC-AGENTS ON THE PROLIFERATION OF CAPILLARY ENDOTHELIAL-CELLS AND TUMOR ANGIOGENESIS IN MURINE BLADDER-CANCER". International Journal of Oncology 6, no. 5 (1995): 1021-1026. https://doi.org/10.3892/ijo.6.5.1021
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