Screening of peptides which suppress the proliferation of transformed cells
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- Published online on: January 1, 1996 https://doi.org/10.3892/ijo.8.1.125
- Pages: 125-129
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Abstract
We have carried out three rounds of screening tests using 239 synthetic tripeptides for the growth-inhibitory activity toward tumor cells and found that those having amino acid sequences of Pro-Thr-Trp or Glu-Arg-Pro effectively inhibit proliferation of transformed cells. These peptides could be the fundamental structures of new types of anticancer drugs.
