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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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April 1996 Volume 8 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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April 1996 Volume 8 Issue 4

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Article

CD44 with variant exons 8-10 in colorectal tumors

  • Authors:
    • T Goi
    • A Yamaguchi
    • K Takeuchi
    • G Nakagawa
    • S Yamashiro
    • K Furukawa
    • T Urano
    • H Shiku
  • View Affiliations / Copyright

    Affiliations: NAGASAKI UNIV,SCH MED,DEPT ONCOL,NAGASAKI 852,JAPAN. FUKUI MED SCH,DEPT SURG 1,FUKUI 91011,JAPAN. MIE UNIV,SCH MED,DEPT INTERNAL MED 2,TSU,MIE 514,JAPAN.
  • Pages: 657-662
    |
    Published online on: April 1, 1996
       https://doi.org/10.3892/ijo.8.4.657
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Abstract

Using a fusion protein encoded by variant exon (v) 8-10 of CD44, a monoclonal antibody (mAb) 44-1V reactive with v9 product was generated. Western immunoblots and reverse transcriptase-polymerase chain reaction/Southern blot revealed that a 130 kilodalton component containing v8-10 products was specifically expressed in colorectal and gastric cancer cell lines. Immunohistological examination of 179 pairs of colorectal cancer and normal tissues revealed that about 47% of cancers expressed the CD44 variant (CD44v8-10), and its expression correlated with hematogenous and lymph node metastasis. These findings suggest the usefulness of CD44v8-10 in the prediction of colorectal cancer metastasis.

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Copy and paste a formatted citation
Spandidos Publications style
Goi T, Yamaguchi A, Takeuchi K, Nakagawa G, Yamashiro S, Furukawa K, Urano T and Shiku H: CD44 with variant exons 8-10 in colorectal tumors. Int J Oncol 8: 657-662, 1996.
APA
Goi, T., Yamaguchi, A., Takeuchi, K., Nakagawa, G., Yamashiro, S., Furukawa, K. ... Shiku, H. (1996). CD44 with variant exons 8-10 in colorectal tumors. International Journal of Oncology, 8, 657-662. https://doi.org/10.3892/ijo.8.4.657
MLA
Goi, T., Yamaguchi, A., Takeuchi, K., Nakagawa, G., Yamashiro, S., Furukawa, K., Urano, T., Shiku, H."CD44 with variant exons 8-10 in colorectal tumors". International Journal of Oncology 8.4 (1996): 657-662.
Chicago
Goi, T., Yamaguchi, A., Takeuchi, K., Nakagawa, G., Yamashiro, S., Furukawa, K., Urano, T., Shiku, H."CD44 with variant exons 8-10 in colorectal tumors". International Journal of Oncology 8, no. 4 (1996): 657-662. https://doi.org/10.3892/ijo.8.4.657
Copy and paste a formatted citation
x
Spandidos Publications style
Goi T, Yamaguchi A, Takeuchi K, Nakagawa G, Yamashiro S, Furukawa K, Urano T and Shiku H: CD44 with variant exons 8-10 in colorectal tumors. Int J Oncol 8: 657-662, 1996.
APA
Goi, T., Yamaguchi, A., Takeuchi, K., Nakagawa, G., Yamashiro, S., Furukawa, K. ... Shiku, H. (1996). CD44 with variant exons 8-10 in colorectal tumors. International Journal of Oncology, 8, 657-662. https://doi.org/10.3892/ijo.8.4.657
MLA
Goi, T., Yamaguchi, A., Takeuchi, K., Nakagawa, G., Yamashiro, S., Furukawa, K., Urano, T., Shiku, H."CD44 with variant exons 8-10 in colorectal tumors". International Journal of Oncology 8.4 (1996): 657-662.
Chicago
Goi, T., Yamaguchi, A., Takeuchi, K., Nakagawa, G., Yamashiro, S., Furukawa, K., Urano, T., Shiku, H."CD44 with variant exons 8-10 in colorectal tumors". International Journal of Oncology 8, no. 4 (1996): 657-662. https://doi.org/10.3892/ijo.8.4.657
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