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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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August-2017 Volume 7 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Medicine International

An International Open Access Journal Devoted to General Medicine.

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Article

Long non‑coding RNA HOTTIP is able to predict poor prognosis in various neoplasms: A meta‑analysis

  • Authors:
    • Ning Jin
    • Ling‑Yun Yang
    • Zi‑Peng Xu
  • View Affiliations / Copyright

    Affiliations: Department of Pathology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210011, P.R. China, Department of Pediatrics, Wuxi Children's Hospital, Wuxi, Jiangsu 214002, P.R. China, Department of General Surgery, Xishan People's Hospital, Wuxi, Jiangsu 214011, P.R. China
  • Pages: 263-266
    |
    Published online on: June 15, 2017
       https://doi.org/10.3892/mco.2017.1293
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Abstract

HOXA distal transcript antisense RNA (HOTTIP), a critical oncogenic long non‑coding RNA, has been reported to be aberrantly regulated in various cancer types. The present meta‑analysis aimed to investigate HOTTIP as a potential clinical applicable prognostic biomarker in malignant neoplasms. Literature collections were performed by searching the electronic databases, PubMed and Web of Science (up to July 20, 2016). All the relevant searches were conducted to identify the association of HOTTIP with the overall survival (OS) rate. A total of six articles consisting of 508 patients were included in the present meta‑analysis. The results suggested that the overexpression of HOTTIP is closely correlated with poor OS (hazard ratio=2.28; 95% confidence interval=1.71‑3.04; P=0.000). In conclusion, the present meta‑analysis has demonstrated that an increased expression level of HOTTIP is correlated with poor OS in different types of cancer, suggesting that HOTTIP potentially serves as a reliable prognostic biomarker in different types of cancer.

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Copy and paste a formatted citation
Spandidos Publications style
Jin N, Yang LY and Xu ZP: Long non‑coding RNA HOTTIP is able to predict poor prognosis in various neoplasms: A meta‑analysis. Mol Clin Oncol 7: 263-266, 2017.
APA
Jin, N., Yang, L., & Xu, Z. (2017). Long non‑coding RNA HOTTIP is able to predict poor prognosis in various neoplasms: A meta‑analysis. Molecular and Clinical Oncology, 7, 263-266. https://doi.org/10.3892/mco.2017.1293
MLA
Jin, N., Yang, L., Xu, Z."Long non‑coding RNA HOTTIP is able to predict poor prognosis in various neoplasms: A meta‑analysis". Molecular and Clinical Oncology 7.2 (2017): 263-266.
Chicago
Jin, N., Yang, L., Xu, Z."Long non‑coding RNA HOTTIP is able to predict poor prognosis in various neoplasms: A meta‑analysis". Molecular and Clinical Oncology 7, no. 2 (2017): 263-266. https://doi.org/10.3892/mco.2017.1293
Copy and paste a formatted citation
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Spandidos Publications style
Jin N, Yang LY and Xu ZP: Long non‑coding RNA HOTTIP is able to predict poor prognosis in various neoplasms: A meta‑analysis. Mol Clin Oncol 7: 263-266, 2017.
APA
Jin, N., Yang, L., & Xu, Z. (2017). Long non‑coding RNA HOTTIP is able to predict poor prognosis in various neoplasms: A meta‑analysis. Molecular and Clinical Oncology, 7, 263-266. https://doi.org/10.3892/mco.2017.1293
MLA
Jin, N., Yang, L., Xu, Z."Long non‑coding RNA HOTTIP is able to predict poor prognosis in various neoplasms: A meta‑analysis". Molecular and Clinical Oncology 7.2 (2017): 263-266.
Chicago
Jin, N., Yang, L., Xu, Z."Long non‑coding RNA HOTTIP is able to predict poor prognosis in various neoplasms: A meta‑analysis". Molecular and Clinical Oncology 7, no. 2 (2017): 263-266. https://doi.org/10.3892/mco.2017.1293
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