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Medicine International
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Print ISSN: 2754-3242 Online ISSN: 2754-1304
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September-October 2026 Volume 6 Issue 5

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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September-October 2026 Volume 6 Issue 5

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Case Report Open Access

Erythrodermic psoriasis with early diagnostic uncertainty requiring multidisciplinary rheumatological management: A case report

  • Authors:
    • Shilpa Raman Danagara
    • Tarun Selvarajan
    • Lavanya Kannekanti
    • Aleeza Qamar
    • Ashley Flowers
    • Sarwat Umer

  • View Affiliations / Copyright

    Affiliations: Department of Internal Medicine, LSU Health Shreveport, Shreveport, LA 71103, USA, Center of Excellence for Arthritis and Rheumatology, LSU Health Shreveport, Shreveport, LA 71103, USA, Department of Pathology, LSU Health Shreveport, Shreveport, LA 71103, USA
    Copyright: © Danagara et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 46
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    Published online on: July 10, 2026
       https://doi.org/10.3892/mi.2026.330
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Abstract

Erythrodermic psoriasis is a rare and potentially life‑threatening variant of psoriasis characterized by diffuse erythema and scaling involving the majority of body surface area. The clinical presentation may overlap with severe cutaneous adverse reactions, such as Stevens‑Johnson syndrome and toxic epidermal necrolysis (TEN), creating diagnostic uncertainty and therapeutic challenges. Standard treatment includes cyclosporine or biological therapy, whereas intravenous immunoglobulin (IVIG) is traditionally reserved for TEN. The present case report describes the case of a 42‑year‑old woman with biopsy‑proven psoriasis and polycythemia vera who presented with rapidly progressive erythroderma involving ~90% of her body surface area following cyclosporine dose escalation. Marked systemic inflammation and TEN‑like features prompted treatment with IVIG at 400 mg/kg/day for 5 consecutive days, resulting in a marked clinical improvement. She was subsequently transitioned to secukinumab for maintenance therapy. The present case report highlights IVIG as a potential rescue therapy in severe erythrodermic psoriasis when diagnostic overlap with TEN exists and rapid disease control is required.

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Copy and paste a formatted citation
Spandidos Publications style
Danagara SR, Selvarajan T, Kannekanti L, Qamar A, Flowers A and Umer S: Erythrodermic psoriasis with early diagnostic uncertainty requiring multidisciplinary rheumatological management: A case report. Med Int 6: 46, 2026.
APA
Danagara, S.R., Selvarajan, T., Kannekanti, L., Qamar, A., Flowers, A., & Umer, S. (2026). Erythrodermic psoriasis with early diagnostic uncertainty requiring multidisciplinary rheumatological management: A case report. Medicine International, 6, 46. https://doi.org/10.3892/mi.2026.330
MLA
Danagara, S. R., Selvarajan, T., Kannekanti, L., Qamar, A., Flowers, A., Umer, S."Erythrodermic psoriasis with early diagnostic uncertainty requiring multidisciplinary rheumatological management: A case report". Medicine International 6.5 (2026): 46.
Chicago
Danagara, S. R., Selvarajan, T., Kannekanti, L., Qamar, A., Flowers, A., Umer, S."Erythrodermic psoriasis with early diagnostic uncertainty requiring multidisciplinary rheumatological management: A case report". Medicine International 6, no. 5 (2026): 46. https://doi.org/10.3892/mi.2026.330
Copy and paste a formatted citation
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Spandidos Publications style
Danagara SR, Selvarajan T, Kannekanti L, Qamar A, Flowers A and Umer S: Erythrodermic psoriasis with early diagnostic uncertainty requiring multidisciplinary rheumatological management: A case report. Med Int 6: 46, 2026.
APA
Danagara, S.R., Selvarajan, T., Kannekanti, L., Qamar, A., Flowers, A., & Umer, S. (2026). Erythrodermic psoriasis with early diagnostic uncertainty requiring multidisciplinary rheumatological management: A case report. Medicine International, 6, 46. https://doi.org/10.3892/mi.2026.330
MLA
Danagara, S. R., Selvarajan, T., Kannekanti, L., Qamar, A., Flowers, A., Umer, S."Erythrodermic psoriasis with early diagnostic uncertainty requiring multidisciplinary rheumatological management: A case report". Medicine International 6.5 (2026): 46.
Chicago
Danagara, S. R., Selvarajan, T., Kannekanti, L., Qamar, A., Flowers, A., Umer, S."Erythrodermic psoriasis with early diagnostic uncertainty requiring multidisciplinary rheumatological management: A case report". Medicine International 6, no. 5 (2026): 46. https://doi.org/10.3892/mi.2026.330
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