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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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July-August 2008 Volume 1 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July-August 2008 Volume 1 Issue 4

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Article

Polymorphisms of the matrix metalloproteinases associated with prostate cancer

  • Authors:
    • Sabrina Thalita Dos Reis
    • Fabiola Elizabeth Villanova
    • Priscila Maria De Andrade
    • José Pontes
    • Iran Amorim Silva
    • Flávio Canelas Canavez
    • Adriana Sañudo
    • Miguel Srougi
    • Kátia Ramos Moreira Leite

  • View Affiliations / Copyright

    Affiliations: Laboratory of Medical Investigation (LIM55), Urology Department, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil. sasareis@gmail.com
  • Pages: 517-520
    |
    Published online on: July 1, 2008
       https://doi.org/10.3892/mmr.1.4.517
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Abstract

Prostate cancer (PCa) is the most common type of malignant tumor in Brazilian males. Single nucleotide polymorphisms (SNPs) have been demonstrated to be present in the promoter region of matrix metalloproteinase (MMP) genes and have been associated with the development and progression of some cancers. In this study, our aim was to investigate the association between the polymorphisms of MMP1, 2, 7, and 9 and susceptibility, and their correlation with the classic prognostic parameters of PCa. For genes MMP1, 2 and 9, the frequencies of the polymorphic homozygote genotypes were higher in the control group than in the PCa group (P<0.0001). We conclude that the MMP1, 2 and 9 polymorphisms are more common in the control group than in patients with PCa, and may have a protective effect in the development of this neoplasia.

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Copy and paste a formatted citation
Spandidos Publications style
Dos Reis ST, Villanova FE, De Andrade PM, Pontes J, Silva IA, Canavez FC, Sañudo A, Srougi M and Leite KR: Polymorphisms of the matrix metalloproteinases associated with prostate cancer. Mol Med Rep 1: 517-520, 2008.
APA
Dos Reis, S.T., Villanova, F.E., De Andrade, P.M., Pontes, J., Silva, I.A., Canavez, F.C. ... Leite, K.R. (2008). Polymorphisms of the matrix metalloproteinases associated with prostate cancer. Molecular Medicine Reports, 1, 517-520. https://doi.org/10.3892/mmr.1.4.517
MLA
Dos Reis, S. T., Villanova, F. E., De Andrade, P. M., Pontes, J., Silva, I. A., Canavez, F. C., Sañudo, A., Srougi, M., Leite, K. R."Polymorphisms of the matrix metalloproteinases associated with prostate cancer". Molecular Medicine Reports 1.4 (2008): 517-520.
Chicago
Dos Reis, S. T., Villanova, F. E., De Andrade, P. M., Pontes, J., Silva, I. A., Canavez, F. C., Sañudo, A., Srougi, M., Leite, K. R."Polymorphisms of the matrix metalloproteinases associated with prostate cancer". Molecular Medicine Reports 1, no. 4 (2008): 517-520. https://doi.org/10.3892/mmr.1.4.517
Copy and paste a formatted citation
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Spandidos Publications style
Dos Reis ST, Villanova FE, De Andrade PM, Pontes J, Silva IA, Canavez FC, Sañudo A, Srougi M and Leite KR: Polymorphisms of the matrix metalloproteinases associated with prostate cancer. Mol Med Rep 1: 517-520, 2008.
APA
Dos Reis, S.T., Villanova, F.E., De Andrade, P.M., Pontes, J., Silva, I.A., Canavez, F.C. ... Leite, K.R. (2008). Polymorphisms of the matrix metalloproteinases associated with prostate cancer. Molecular Medicine Reports, 1, 517-520. https://doi.org/10.3892/mmr.1.4.517
MLA
Dos Reis, S. T., Villanova, F. E., De Andrade, P. M., Pontes, J., Silva, I. A., Canavez, F. C., Sañudo, A., Srougi, M., Leite, K. R."Polymorphisms of the matrix metalloproteinases associated with prostate cancer". Molecular Medicine Reports 1.4 (2008): 517-520.
Chicago
Dos Reis, S. T., Villanova, F. E., De Andrade, P. M., Pontes, J., Silva, I. A., Canavez, F. C., Sañudo, A., Srougi, M., Leite, K. R."Polymorphisms of the matrix metalloproteinases associated with prostate cancer". Molecular Medicine Reports 1, no. 4 (2008): 517-520. https://doi.org/10.3892/mmr.1.4.517
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