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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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July 2012 Volume 6 Issue 1

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

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Review Open Access

Angiogenic factors in placentas from pregnancies complicated by fetal growth restriction (Review)

  • Authors:
    • Victor Gourvas
    • Efterpi Dalpa
    • Anastasia Konstantinidou
    • Nikolaos Vrachnis
    • Demetrios A. Spandidos
    • Stavros Sifakis

  • View Affiliations / Copyright

    Affiliations: Department of Virology, Medical School, University of Crete, Heraklion, Crete, Greece, First Department of Pathology, University of Athens, Athens, Greece, Second Department of Obstetrics and Gynecology, University of Athens, Athens, Greece, Department of Obstetrics and Gynecology, University Hospital of Heraklion, Crete, Greece
  • Pages: 23-27
    |
    Published online on: May 2, 2012
       https://doi.org/10.3892/mmr.2012.898
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Abstract

The placenta is the organ that is responsible for providing the developing fetus with all the nutrients necessary for its growth and is also responsible for removing fetal waste. Placentation is a crucial process that includes angiogenesis. Angiogenesis involves not only the fetal circulation, but also placental and endometrial vascular changes. In this study, we review the literature regarding any impairment in the angiogenic process in placentas from pregnancies complicated by fetal growth restriction (FGR). Angiogenesis is regulated by a list of factors, also known as growth factors, such as the vascular endothelial growth factor (VEGF), the placental growth factor (PlGF) and the basic fibroblastic growth factor (bFGF), as well as the partial pressure of oxygen in the fetoplacental vessels. Other factors, such as transcriptional factors, also play a pivotal role, controlling the above-mentioned growth factors. Alterations in these pathways have been described in cases of growth-restricted fetuses. In this review, we provide an insight into these processes and identify the most crucial factors involved.

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Copy and paste a formatted citation
Spandidos Publications style
Gourvas V, Dalpa E, Konstantinidou A, Vrachnis N, Spandidos DA and Sifakis S: Angiogenic factors in placentas from pregnancies complicated by fetal growth restriction (Review). Mol Med Rep 6: 23-27, 2012.
APA
Gourvas, V., Dalpa, E., Konstantinidou, A., Vrachnis, N., Spandidos, D.A., & Sifakis, S. (2012). Angiogenic factors in placentas from pregnancies complicated by fetal growth restriction (Review). Molecular Medicine Reports, 6, 23-27. https://doi.org/10.3892/mmr.2012.898
MLA
Gourvas, V., Dalpa, E., Konstantinidou, A., Vrachnis, N., Spandidos, D. A., Sifakis, S."Angiogenic factors in placentas from pregnancies complicated by fetal growth restriction (Review)". Molecular Medicine Reports 6.1 (2012): 23-27.
Chicago
Gourvas, V., Dalpa, E., Konstantinidou, A., Vrachnis, N., Spandidos, D. A., Sifakis, S."Angiogenic factors in placentas from pregnancies complicated by fetal growth restriction (Review)". Molecular Medicine Reports 6, no. 1 (2012): 23-27. https://doi.org/10.3892/mmr.2012.898
Copy and paste a formatted citation
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Spandidos Publications style
Gourvas V, Dalpa E, Konstantinidou A, Vrachnis N, Spandidos DA and Sifakis S: Angiogenic factors in placentas from pregnancies complicated by fetal growth restriction (Review). Mol Med Rep 6: 23-27, 2012.
APA
Gourvas, V., Dalpa, E., Konstantinidou, A., Vrachnis, N., Spandidos, D.A., & Sifakis, S. (2012). Angiogenic factors in placentas from pregnancies complicated by fetal growth restriction (Review). Molecular Medicine Reports, 6, 23-27. https://doi.org/10.3892/mmr.2012.898
MLA
Gourvas, V., Dalpa, E., Konstantinidou, A., Vrachnis, N., Spandidos, D. A., Sifakis, S."Angiogenic factors in placentas from pregnancies complicated by fetal growth restriction (Review)". Molecular Medicine Reports 6.1 (2012): 23-27.
Chicago
Gourvas, V., Dalpa, E., Konstantinidou, A., Vrachnis, N., Spandidos, D. A., Sifakis, S."Angiogenic factors in placentas from pregnancies complicated by fetal growth restriction (Review)". Molecular Medicine Reports 6, no. 1 (2012): 23-27. https://doi.org/10.3892/mmr.2012.898
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