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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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July-August 2010 Volume 3 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July-August 2010 Volume 3 Issue 4

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Article

The functional role of dendritic cells in atherogenesis (Review)

  • Authors:
    • Paolo Puddu
    • Giovanni M. Puddu
    • Eleonora Cravero
    • Silvia Muscari
    • Antonio Muscari

  • View Affiliations / Copyright

    Affiliations: Department of Internal Medicine, Aging and Nephrological Diseases, University of Bologna and S. Orsola-Malpighi Hospital, 40138 Bologna, Italy
  • Pages: 551-554
    |
    Published online on: July 1, 2010
       https://doi.org/10.3892/mmr_00000295
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Abstract

Accumulating evidence suggests that dendritic cells (DCs) play a crucial role in the generation and progression of atherosclerosis (ATS), a lipid-related immuno-inflammatory disease. DCs have the ability to process and present antigens (mainly oxidized low-density lipoproteins, heat shock proteins and fragments of necrotic or apoptotic cells) to naive T cells, and the activation of T cells is a key step for the progression of atherosclerotic disease. The existence of some distinct DC subtypes has now become evident. The main categories of DC subsets are the ‘conventional or myeloid’ and the ‘plasmacytoid’, which differ in toll-like receptor type and site of expression, pathogens and antigens recognized, and effector cytokines and functions. Studies on the potential impact of DCs in the pathogenesis of ATS may lead to novel therapies to regulate the immunoreactions occurring in atherogenesis. In particular, diltiazem, peroxisome proliferator activated receptor agonists and statins have been shown to protect endothelial cell function by inhibiting DCs, a mechanism that may play a significant role in the prevention of ATS.

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Copy and paste a formatted citation
Spandidos Publications style
Puddu P, Puddu GM, Cravero E, Muscari S and Muscari A: The functional role of dendritic cells in atherogenesis (Review) . Mol Med Rep 3: 551-554, 2010.
APA
Puddu, P., Puddu, G.M., Cravero, E., Muscari, S., & Muscari, A. (2010). The functional role of dendritic cells in atherogenesis (Review) . Molecular Medicine Reports, 3, 551-554. https://doi.org/10.3892/mmr_00000295
MLA
Puddu, P., Puddu, G. M., Cravero, E., Muscari, S., Muscari, A."The functional role of dendritic cells in atherogenesis (Review) ". Molecular Medicine Reports 3.4 (2010): 551-554.
Chicago
Puddu, P., Puddu, G. M., Cravero, E., Muscari, S., Muscari, A."The functional role of dendritic cells in atherogenesis (Review) ". Molecular Medicine Reports 3, no. 4 (2010): 551-554. https://doi.org/10.3892/mmr_00000295
Copy and paste a formatted citation
x
Spandidos Publications style
Puddu P, Puddu GM, Cravero E, Muscari S and Muscari A: The functional role of dendritic cells in atherogenesis (Review) . Mol Med Rep 3: 551-554, 2010.
APA
Puddu, P., Puddu, G.M., Cravero, E., Muscari, S., & Muscari, A. (2010). The functional role of dendritic cells in atherogenesis (Review) . Molecular Medicine Reports, 3, 551-554. https://doi.org/10.3892/mmr_00000295
MLA
Puddu, P., Puddu, G. M., Cravero, E., Muscari, S., Muscari, A."The functional role of dendritic cells in atherogenesis (Review) ". Molecular Medicine Reports 3.4 (2010): 551-554.
Chicago
Puddu, P., Puddu, G. M., Cravero, E., Muscari, S., Muscari, A."The functional role of dendritic cells in atherogenesis (Review) ". Molecular Medicine Reports 3, no. 4 (2010): 551-554. https://doi.org/10.3892/mmr_00000295
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