[Corrigendum] Chloroquine potentiates the anticancer effect of sunitinib on renal cell carcinoma by inhibiting autophagy and inducing apoptosis

Li,Man-Li; Xu,You-Zhi; Lu,Wen-Jie; Li,Yong-Huai; Tan,Shi-Sheng; Lin,Hong-Jun; Wu,Tian-Ming; Li,Yan; Wang,Si-Ying; Zhao,Ying-Lan

doi:10.3892/ol.2024.14403

June-2024 Volume 27 Issue 6

Full Size Image

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

June-2024 Volume 27 Issue 6

Full Size Image

Correction Open Access

[Corrigendum] Chloroquine potentiates the anticancer effect of sunitinib on renal cell carcinoma by inhibiting autophagy and inducing apoptosis

Authors:
- Man-Li Li
- You-Zhi Xu
- Wen-Jie Lu
- Yong-Huai Li
- Shi-Sheng Tan
- Hong-Jun Lin
- Tian-Ming Wu
- Yan Li
- Si-Ying Wang
- Ying-Lan Zhao
View Affiliations / Copyright

Affiliations: Cancer Center, West China Hospital, West China Medical School, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, P.R. China, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui 230032, P.R. China, Department of Respiratory Disease, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China, Department of Oncology, Guizhou People's Hospital, Guiyang, Guizhou 510002, P.R. China

Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
Article Number: 270
|
Published online on: April 17, 2024

https://doi.org/10.3892/ol.2024.14403
Expand metrics +

Article

Oncol Lett 15: [Related article:] 2839–2846, 2018; DOI: 10.3892/ol.2017.7635

Following the publication of the above article, an interested reader contacted the Editorial Office to inform us that, in Fig. 4D on p. 2845 showing the results of TUNEL assay experiments, the ‘Control’ and ‘CQ’ data panels appeared to be strikingly similar, such that these data may have been derived from the same original source, where the data were intended to show the results from differently performed experiments.

Figure 4.

Sunitinib induces autophagy by inhibiting the Akt/mTOR/p70S6K signaling pathway, and may inhibit the growth of OS-RC-2 tumors in vivo. (A) Protein expression of PI3K, AKT, p-AKT, TSC2, p-TSC2, mTOR, p-mTOR, p70S6K and p-p70S6K in OS-RC-2 cells. (B) The inhibitory effect on the proliferation of OS-RC-2 cells established in nude BALB/c mice following CQ (20 mg/kg/day intravenously), sunitinib (40 mg/kg/day orally) or both. The data were expressed as the mean ± SD. (C) Mouse body weight was not significantly altered following sunitinib and CQ co-treatment. (D) A terminal dexynucleotidyl transferase-mediated dUTP nick end labeling assay was performed to measure the induction of apoptosis. (E) Tumor cell proliferation in different groups was analyzed by the staining of phosphorylated histone H3. (F) Tumor cell autophagy in different groups was analyzed by LC3-II staining. Data represent the means ± SD or are representative of ≥3 independent experiments (magnification, ×200). *P<0.05 and **P<0.01 compared with control. PI3K, phosphoinositide 3-kinase; p-, phosphorylated; TSC2, tuberous sclerosis complex 2; mTOR, mechanistic target of rapamycin; p70S6K, p70S6 kinase; CQ, chloroquine; SD, standard deviation.

The authors have consulted their original data, and were able to identify where the error occurred in terms of the data selection for Fig. 4B. The corrected version of Fig. 4, showing the correct data for the ‘Control’ panel in Fig. 4D, is shown on the next page. All the authors approve of the publication of this corrigendum, and the authors are grateful to the Editor of Oncology Letters for granting them the opportunity to publish this. The authors also apologize to the readership for any inconvenience caused.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

[Corrigendum] Chloroquine potentiates the anticancer effect of sunitinib on renal cell carcinoma by inhibiting autophagy and inducing apoptosis

This article is mentioned in:

Article

Figure 4.

Related Articles