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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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January 1994 Volume 1 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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January 1994 Volume 1 Issue 1

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Article

SUPPRESSION OF TUMORIGENESIS AND TUMOR-GROWTH OF MOUSE MAMMARY-GLANDS BY A TRADITIONAL CHINESE HERBAL MEDICINE, SHO-SAIKO-TO

  • Authors:
    • T NAKAYAMA
    • S SAKAMOTO
    • T MORI
    • H NAGASAWA

  • View Affiliations / Copyright

    Affiliations: TOKYO MED & DENT UNIV,MED RES INST,BUNKYO KU,TOKYO 113,JAPAN. TOKYO MED & DENT UNIV,DEPT INTERNAL MED 1,TOKYO 113,JAPAN. UNIV TOKYO,FAC SCI,INST ZOOL,TOKYO 113,JAPAN. MEIJI UNIV,EXPTL ANIM RES LAB,TOKYO,JAPAN.
  • Pages: 75-78
    |
    Published online on: January 1, 1994
       https://doi.org/10.3892/or.1.1.75
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Abstract

Hyperplastic alveolar nodule (HAN) is a representative preneoplastic state in mammary glands of mice. We investigated the effect of Sho-saiko-to (SST; a Japanese modified traditional Chinese herbal medicine containing seven medicinal plants) on the formation and growth of HAN and mammary tumour growth in SHN virgin mice which showed a high incidence of spontaneous mammary tumours. Chronic oral administration of SST reduced the number and the area of HAN and mammary thymidylate synthetase (TS) activity with slight decrease of serum prolactin level. In the established mammary tumours of mice, 20-day administration of SST reduced the activity of TS and thymidine kinase (TK) with slight reduction of serum prolactin level, though the significant change of mammary-tumour growth was not observed. These results indicate that SST may prevent the mammary tumourigenesis by suppression of the de novo pathway for pyrimidine nucleotide synthesis and the mammary tumour growth by suppression of the salvage pathway as well as the de novo pathway in mice.

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Copy and paste a formatted citation
Spandidos Publications style
NAKAYAMA T, SAKAMOTO S, MORI T and NAGASAWA H: SUPPRESSION OF TUMORIGENESIS AND TUMOR-GROWTH OF MOUSE MAMMARY-GLANDS BY A TRADITIONAL CHINESE HERBAL MEDICINE, SHO-SAIKO-TO. Oncol Rep 1: 75-78, 1994.
APA
NAKAYAMA, T., SAKAMOTO, S., MORI, T., & NAGASAWA, H. (1994). SUPPRESSION OF TUMORIGENESIS AND TUMOR-GROWTH OF MOUSE MAMMARY-GLANDS BY A TRADITIONAL CHINESE HERBAL MEDICINE, SHO-SAIKO-TO. Oncology Reports, 1, 75-78. https://doi.org/10.3892/or.1.1.75
MLA
NAKAYAMA, T., SAKAMOTO, S., MORI, T., NAGASAWA, H."SUPPRESSION OF TUMORIGENESIS AND TUMOR-GROWTH OF MOUSE MAMMARY-GLANDS BY A TRADITIONAL CHINESE HERBAL MEDICINE, SHO-SAIKO-TO". Oncology Reports 1.1 (1994): 75-78.
Chicago
NAKAYAMA, T., SAKAMOTO, S., MORI, T., NAGASAWA, H."SUPPRESSION OF TUMORIGENESIS AND TUMOR-GROWTH OF MOUSE MAMMARY-GLANDS BY A TRADITIONAL CHINESE HERBAL MEDICINE, SHO-SAIKO-TO". Oncology Reports 1, no. 1 (1994): 75-78. https://doi.org/10.3892/or.1.1.75
Copy and paste a formatted citation
x
Spandidos Publications style
NAKAYAMA T, SAKAMOTO S, MORI T and NAGASAWA H: SUPPRESSION OF TUMORIGENESIS AND TUMOR-GROWTH OF MOUSE MAMMARY-GLANDS BY A TRADITIONAL CHINESE HERBAL MEDICINE, SHO-SAIKO-TO. Oncol Rep 1: 75-78, 1994.
APA
NAKAYAMA, T., SAKAMOTO, S., MORI, T., & NAGASAWA, H. (1994). SUPPRESSION OF TUMORIGENESIS AND TUMOR-GROWTH OF MOUSE MAMMARY-GLANDS BY A TRADITIONAL CHINESE HERBAL MEDICINE, SHO-SAIKO-TO. Oncology Reports, 1, 75-78. https://doi.org/10.3892/or.1.1.75
MLA
NAKAYAMA, T., SAKAMOTO, S., MORI, T., NAGASAWA, H."SUPPRESSION OF TUMORIGENESIS AND TUMOR-GROWTH OF MOUSE MAMMARY-GLANDS BY A TRADITIONAL CHINESE HERBAL MEDICINE, SHO-SAIKO-TO". Oncology Reports 1.1 (1994): 75-78.
Chicago
NAKAYAMA, T., SAKAMOTO, S., MORI, T., NAGASAWA, H."SUPPRESSION OF TUMORIGENESIS AND TUMOR-GROWTH OF MOUSE MAMMARY-GLANDS BY A TRADITIONAL CHINESE HERBAL MEDICINE, SHO-SAIKO-TO". Oncology Reports 1, no. 1 (1994): 75-78. https://doi.org/10.3892/or.1.1.75
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