CYTODIFFERENTIATION INDUCERS AS ANTICANCER AGENTS (REVIEW)
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- Published online on: May 1, 1994 https://doi.org/10.3892/or.1.3.481
- Pages: 481-487
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Abstract
Several successful applications of differentiating agents in leukemic diseases, led to a regained interest in differentiation therapy. In this report we focus on novel classes of natural and synthetic compounds, which were not extensively reviewed and have a promising potential as anticancer agents e.g. protein kinase analogues, butyric acid, vitamin D-3 and purine and pyrimidine derivatives. The biological activities, preclinical and clinical studies of these agents are described.
