ANEUPLOID CELLS IN BENIGN BREAST-LESIONS MONITORED BY FLOW-CYTOMETRY

  • Authors:
    • R DEVITA
    • P ELEUTERI
    • D CAVALLO
    • D FORTE
    • MG GROLLINO
    • O MAGGI
    • A CALUGI
  • View Affiliations

  • Published online on: May 1, 1994     https://doi.org/10.3892/or.1.3.513
  • Pages: 513-517
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Abstract

It has been observed that various types of benign breast disease are associated to an increased risk of breast cancer. The biological significance of this association remains unclear: both benign and malignant lesions could independently have a common set of risk factors. The cellular DNA content of biopsy samples from 47 breast benign lesions was analyzed by flow cytometry. Flow cytometric measurements evidenced that 11/47 cases showed at least one aneuploid cell subpopulation. The presence of aneuploid subpopulations in benign lesions could be related to an unknown cellular alteration predisponding the developement of benign and malignant lesions independently.

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May 1994
Volume 1 Issue 3

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
DEVITA R, ELEUTERI P, CAVALLO D, FORTE D, GROLLINO M, MAGGI O and CALUGI A: ANEUPLOID CELLS IN BENIGN BREAST-LESIONS MONITORED BY FLOW-CYTOMETRY. Oncol Rep 1: 513-517, 1994
APA
DEVITA, R., ELEUTERI, P., CAVALLO, D., FORTE, D., GROLLINO, M., MAGGI, O., & CALUGI, A. (1994). ANEUPLOID CELLS IN BENIGN BREAST-LESIONS MONITORED BY FLOW-CYTOMETRY. Oncology Reports, 1, 513-517. https://doi.org/10.3892/or.1.3.513
MLA
DEVITA, R., ELEUTERI, P., CAVALLO, D., FORTE, D., GROLLINO, M., MAGGI, O., CALUGI, A."ANEUPLOID CELLS IN BENIGN BREAST-LESIONS MONITORED BY FLOW-CYTOMETRY". Oncology Reports 1.3 (1994): 513-517.
Chicago
DEVITA, R., ELEUTERI, P., CAVALLO, D., FORTE, D., GROLLINO, M., MAGGI, O., CALUGI, A."ANEUPLOID CELLS IN BENIGN BREAST-LESIONS MONITORED BY FLOW-CYTOMETRY". Oncology Reports 1, no. 3 (1994): 513-517. https://doi.org/10.3892/or.1.3.513