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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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May 1994 Volume 1 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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May 1994 Volume 1 Issue 3

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Article

COMPARATIVE-STUDIES ON THE ANTI-INVASIVE EFFECTS OF RETINOIC ACID AND STAUROSPORINE

  • Authors:
    • P POPOWICZ
    • S LINDER
  • View Affiliations / Copyright

    Affiliations: KAROLINSKA HOSP & INST,RADIUMHEMMET,DEPT GEN ONCOL,DIV EXPTL ONCOL,S-17176 STOCKHOLM,SWEDEN.
  • Pages: 529-532
    |
    Published online on: May 1, 1994
       https://doi.org/10.3892/or.1.3.529
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Abstract

Retinoic acid and the protein kinase C inhibitor staurosporine have been reported to inhibit the invasiveness of tumor cells and may potentially be used to prevent metastatic disease. We report that retinoic acid reduced the invasiveness of 6 of 6 ras-transformed rat fibroblast cell lines and that inhibition did not require expression of the c-Jun component of AP-1. In contrast, staurosporine reduced the invasiveness of only 1 of 4 ras-transformed cell lines. The effect of staurosporine on the invasiveness of human tumor cell lines varied with cell type and length of treatment. We conclude that retinoic acid, but not necessarily staurosporine, decreases the invasiveness of ras-transformed fibroblasts.

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Copy and paste a formatted citation
Spandidos Publications style
POPOWICZ P and LINDER S: COMPARATIVE-STUDIES ON THE ANTI-INVASIVE EFFECTS OF RETINOIC ACID AND STAUROSPORINE. Oncol Rep 1: 529-532, 1994.
APA
POPOWICZ, P., & LINDER, S. (1994). COMPARATIVE-STUDIES ON THE ANTI-INVASIVE EFFECTS OF RETINOIC ACID AND STAUROSPORINE. Oncology Reports, 1, 529-532. https://doi.org/10.3892/or.1.3.529
MLA
POPOWICZ, P., LINDER, S."COMPARATIVE-STUDIES ON THE ANTI-INVASIVE EFFECTS OF RETINOIC ACID AND STAUROSPORINE". Oncology Reports 1.3 (1994): 529-532.
Chicago
POPOWICZ, P., LINDER, S."COMPARATIVE-STUDIES ON THE ANTI-INVASIVE EFFECTS OF RETINOIC ACID AND STAUROSPORINE". Oncology Reports 1, no. 3 (1994): 529-532. https://doi.org/10.3892/or.1.3.529
Copy and paste a formatted citation
x
Spandidos Publications style
POPOWICZ P and LINDER S: COMPARATIVE-STUDIES ON THE ANTI-INVASIVE EFFECTS OF RETINOIC ACID AND STAUROSPORINE. Oncol Rep 1: 529-532, 1994.
APA
POPOWICZ, P., & LINDER, S. (1994). COMPARATIVE-STUDIES ON THE ANTI-INVASIVE EFFECTS OF RETINOIC ACID AND STAUROSPORINE. Oncology Reports, 1, 529-532. https://doi.org/10.3892/or.1.3.529
MLA
POPOWICZ, P., LINDER, S."COMPARATIVE-STUDIES ON THE ANTI-INVASIVE EFFECTS OF RETINOIC ACID AND STAUROSPORINE". Oncology Reports 1.3 (1994): 529-532.
Chicago
POPOWICZ, P., LINDER, S."COMPARATIVE-STUDIES ON THE ANTI-INVASIVE EFFECTS OF RETINOIC ACID AND STAUROSPORINE". Oncology Reports 1, no. 3 (1994): 529-532. https://doi.org/10.3892/or.1.3.529
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