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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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May 1994 Volume 1 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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May 1994 Volume 1 Issue 3

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Article

P(185/HER2) AND PS2 PROTEIN OVEREXPRESSION IN BREAST-CANCER SPECIMENS - IMPROVEMENT FOR PREDICTION OF RESPONSE TO ENDOCRINE THERAPY

  • Authors:
    • K LOAICIGA
    • MW BECKMANN
    • D NIEDERACHER
    • B TUTSCHECK
    • K ENGELS
    • W KLOCKENBUSCH
    • HG SCHNURCH
    • HG BENDER

  • View Affiliations / Copyright

    Affiliations: UNIV DUSSELDORF,FRAUENKLIN,DEPT OBSTET & GYNECOL,D-40225 DUSSELDORF,GERMANY. UNIV DUSSELDORF,BIOL MED FORSCHUNGZENTRUM,DUSSELDORF,GERMANY.
  • Pages: 625-629
    |
    Published online on: May 1, 1994
       https://doi.org/10.3892/or.1.3.625
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Abstract

Simultaneous analyses of p(185/Her2) and pS2 protein expression in breast cancer is discussed to add information about prognosis and response to endocrine treatment. In a retrospective study, expression of p(185/Her2) and pS2 protein were detected by immunohistochemistry in paraffinembedded, formalin-fixed sections of 219 primary breast cancers. Median age was 56.6 years, median follow-up 168 months. Results were correlated with clinical parameters and steroid receptor status. ER was positive in 55%, PgR in 54% of the tumors. ER correlated inversely with tumor size, and with tumor grade. pS2 was detected in 54% of the tumors, but showed no correlations with other parameters. p(185/Her2) was present in 24% of the tumors and correlated positively with tumor size. pS2 and ER or PgR status correlated (p<0.001). In the sub-group of negative steroid receptors and positive pS2 a qualitative significant difference for p(185/Her2) expression was seen. ER, pS2 and p(185/Her2) status had no prognostic impact on disease-free or overall survival; PgR status correlated with clinical outcome.

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Copy and paste a formatted citation
Spandidos Publications style
LOAICIGA K, BECKMANN M, NIEDERACHER D, TUTSCHECK B, ENGELS K, KLOCKENBUSCH W, SCHNURCH H and BENDER H: P(185/HER2) AND PS2 PROTEIN OVEREXPRESSION IN BREAST-CANCER SPECIMENS - IMPROVEMENT FOR PREDICTION OF RESPONSE TO ENDOCRINE THERAPY. Oncol Rep 1: 625-629, 1994.
APA
LOAICIGA, K., BECKMANN, M., NIEDERACHER, D., TUTSCHECK, B., ENGELS, K., KLOCKENBUSCH, W. ... BENDER, H. (1994). P(185/HER2) AND PS2 PROTEIN OVEREXPRESSION IN BREAST-CANCER SPECIMENS - IMPROVEMENT FOR PREDICTION OF RESPONSE TO ENDOCRINE THERAPY. Oncology Reports, 1, 625-629. https://doi.org/10.3892/or.1.3.625
MLA
LOAICIGA, K., BECKMANN, M., NIEDERACHER, D., TUTSCHECK, B., ENGELS, K., KLOCKENBUSCH, W., SCHNURCH, H., BENDER, H."P(185/HER2) AND PS2 PROTEIN OVEREXPRESSION IN BREAST-CANCER SPECIMENS - IMPROVEMENT FOR PREDICTION OF RESPONSE TO ENDOCRINE THERAPY". Oncology Reports 1.3 (1994): 625-629.
Chicago
LOAICIGA, K., BECKMANN, M., NIEDERACHER, D., TUTSCHECK, B., ENGELS, K., KLOCKENBUSCH, W., SCHNURCH, H., BENDER, H."P(185/HER2) AND PS2 PROTEIN OVEREXPRESSION IN BREAST-CANCER SPECIMENS - IMPROVEMENT FOR PREDICTION OF RESPONSE TO ENDOCRINE THERAPY". Oncology Reports 1, no. 3 (1994): 625-629. https://doi.org/10.3892/or.1.3.625
Copy and paste a formatted citation
x
Spandidos Publications style
LOAICIGA K, BECKMANN M, NIEDERACHER D, TUTSCHECK B, ENGELS K, KLOCKENBUSCH W, SCHNURCH H and BENDER H: P(185/HER2) AND PS2 PROTEIN OVEREXPRESSION IN BREAST-CANCER SPECIMENS - IMPROVEMENT FOR PREDICTION OF RESPONSE TO ENDOCRINE THERAPY. Oncol Rep 1: 625-629, 1994.
APA
LOAICIGA, K., BECKMANN, M., NIEDERACHER, D., TUTSCHECK, B., ENGELS, K., KLOCKENBUSCH, W. ... BENDER, H. (1994). P(185/HER2) AND PS2 PROTEIN OVEREXPRESSION IN BREAST-CANCER SPECIMENS - IMPROVEMENT FOR PREDICTION OF RESPONSE TO ENDOCRINE THERAPY. Oncology Reports, 1, 625-629. https://doi.org/10.3892/or.1.3.625
MLA
LOAICIGA, K., BECKMANN, M., NIEDERACHER, D., TUTSCHECK, B., ENGELS, K., KLOCKENBUSCH, W., SCHNURCH, H., BENDER, H."P(185/HER2) AND PS2 PROTEIN OVEREXPRESSION IN BREAST-CANCER SPECIMENS - IMPROVEMENT FOR PREDICTION OF RESPONSE TO ENDOCRINE THERAPY". Oncology Reports 1.3 (1994): 625-629.
Chicago
LOAICIGA, K., BECKMANN, M., NIEDERACHER, D., TUTSCHECK, B., ENGELS, K., KLOCKENBUSCH, W., SCHNURCH, H., BENDER, H."P(185/HER2) AND PS2 PROTEIN OVEREXPRESSION IN BREAST-CANCER SPECIMENS - IMPROVEMENT FOR PREDICTION OF RESPONSE TO ENDOCRINE THERAPY". Oncology Reports 1, no. 3 (1994): 625-629. https://doi.org/10.3892/or.1.3.625
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