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INHIBITORY EFFECTS OF COMBINED ADMINISTRATION OF UFT AND KRESTIN ON INTRAPERITONEAL METASTASES IN MICE

  • Authors:
    • S TAKENOSHITA
    • T HASHIZUME
    • T ASAO
    • JI NAKAMURA
    • Y YAJIMA
    • K SHINOZAKI
    • Y SHITARA
    • K TSUKADA
    • H KOITABASHI
    • R KATOH
    • Y NAGAMACHI

  • View Affiliations

  • Published online on: July 1, 1994     https://doi.org/10.3892/or.1.4.727
  • Pages: 727-730
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Abstract

In this study we investigated the effect of combined administration of UFT and Krestin (PSK) on the growth of intraperitoneal metastasis and temporal changes in the immune-endocrine system under this immunochemotherapy. At 7 days, Plasma ACTH levels of the PSK group were significantly lower than that of the control group (p<0.01). At 14 days, the tumor weight in the combined and the PSK alone group was significantly decreased, compared to the control group (p<0.05). Serum IAP levels of the UFT group were significantly lower than that of the control group (p<0.05). Serum cortisol levels of the combined group were lower than that of the other groups.

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July 1994
Volume 1 Issue 4

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
TAKENOSHITA S, HASHIZUME T, ASAO T, NAKAMURA J, YAJIMA Y, SHINOZAKI K, SHITARA Y, TSUKADA K, KOITABASHI H, KATOH R, KATOH R, et al: INHIBITORY EFFECTS OF COMBINED ADMINISTRATION OF UFT AND KRESTIN ON INTRAPERITONEAL METASTASES IN MICE. Oncol Rep 1: 727-730, 1994
APA
TAKENOSHITA, S., HASHIZUME, T., ASAO, T., NAKAMURA, J., YAJIMA, Y., SHINOZAKI, K. ... NAGAMACHI, Y. (1994). INHIBITORY EFFECTS OF COMBINED ADMINISTRATION OF UFT AND KRESTIN ON INTRAPERITONEAL METASTASES IN MICE. Oncology Reports, 1, 727-730. https://doi.org/10.3892/or.1.4.727
MLA
TAKENOSHITA, S., HASHIZUME, T., ASAO, T., NAKAMURA, J., YAJIMA, Y., SHINOZAKI, K., SHITARA, Y., TSUKADA, K., KOITABASHI, H., KATOH, R., NAGAMACHI, Y."INHIBITORY EFFECTS OF COMBINED ADMINISTRATION OF UFT AND KRESTIN ON INTRAPERITONEAL METASTASES IN MICE". Oncology Reports 1.4 (1994): 727-730.
Chicago
TAKENOSHITA, S., HASHIZUME, T., ASAO, T., NAKAMURA, J., YAJIMA, Y., SHINOZAKI, K., SHITARA, Y., TSUKADA, K., KOITABASHI, H., KATOH, R., NAGAMACHI, Y."INHIBITORY EFFECTS OF COMBINED ADMINISTRATION OF UFT AND KRESTIN ON INTRAPERITONEAL METASTASES IN MICE". Oncology Reports 1, no. 4 (1994): 727-730. https://doi.org/10.3892/or.1.4.727