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DIFFERENT CHEMOSENSITIVITY OF PRE AND POSTMENOPAUSAL BREAST-CANCER CELLS

  • Authors:
    • Y IKEDA
    • M OGITA
    • H NAITOU
    • H AOKI
    • K IKUTA
    • H SASAKI
    • H ISHIMURA

  • View Affiliations

  • Published online on: November 1, 1994     https://doi.org/10.3892/or.1.6.1093
  • Pages: 1093-1096
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
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Abstract

In order to refine our adjuvant chemotherapy against locally advanced breast cancer, an anticancer drug sensitivity test, using the MTT assay was conducted with biopsy specimens of human breast cancer obtained prior to therapy. Dose-dependent sensitivity was observed with all tested agents: cisplatinum, mitomycin C, methotrexate and doxorubicin. The sensitivity of the premenopausal specimens to the effects of mitomycin C and doxorubicin varied widely. When selecting chemotherapeutic agents to combat breast cancer, this variation in drug sensitivity based on menopausal status and patient age should be considered.

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November 1994
Volume 1 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

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  • Journal Metrics
  • Impact Factor: 4.2
  • Ranked Oncology
    (total number of cites)
  • CiteScore: 8.4
  • CiteScore Rank: Q1: #68/366 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.786
  • SCImago Journal Rank (SJR): 0.812
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Spandidos Publications style
IKEDA Y, OGITA M, NAITOU H, AOKI H, IKUTA K, SASAKI H and ISHIMURA H: DIFFERENT CHEMOSENSITIVITY OF PRE AND POSTMENOPAUSAL BREAST-CANCER CELLS. Oncol Rep 1: 1093-1096, 1994
APA
IKEDA, Y., OGITA, M., NAITOU, H., AOKI, H., IKUTA, K., SASAKI, H., & ISHIMURA, H. (1994). DIFFERENT CHEMOSENSITIVITY OF PRE AND POSTMENOPAUSAL BREAST-CANCER CELLS. Oncology Reports, 1, 1093-1096. https://doi.org/10.3892/or.1.6.1093
MLA
IKEDA, Y., OGITA, M., NAITOU, H., AOKI, H., IKUTA, K., SASAKI, H., ISHIMURA, H."DIFFERENT CHEMOSENSITIVITY OF PRE AND POSTMENOPAUSAL BREAST-CANCER CELLS". Oncology Reports 1.6 (1994): 1093-1096.
Chicago
IKEDA, Y., OGITA, M., NAITOU, H., AOKI, H., IKUTA, K., SASAKI, H., ISHIMURA, H."DIFFERENT CHEMOSENSITIVITY OF PRE AND POSTMENOPAUSAL BREAST-CANCER CELLS". Oncology Reports 1, no. 6 (1994): 1093-1096. https://doi.org/10.3892/or.1.6.1093