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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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November 1994 Volume 1 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November 1994 Volume 1 Issue 6

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Article

DETECTION OF HSV, CMV AND EBV BY THE POLYMERASE CHAIN-REACTION TECHNIQUE IN PATIENTS WITH INFLAMMATORY EYE-DISEASES

  • Authors:
    • M ERGAZAKI
    • G XINARIANOS
    • A GIANNOUDIS
    • N MARKOMICHELAKIS
    • J TSAMPARLAKIS
    • DA SPANDIDOS

  • View Affiliations / Copyright

    Affiliations: NATL HELLEN RES FDN,INST BIOL RES & BIOTECHNOL,GR-11635 ATHENS,GREECE. UNIV CRETE,SCH MED,CLIN VIROL LAB,IRAKLION,GREECE. GEN HOSP ATHENS,OPHTHALMOL CLIN,ATHENS,GREECE. UNIV HOSP HERAKLION,OPHTHALMOL CLIN,IRAKLION,GREECE.
  • Pages: 1207-1210
    |
    Published online on: November 1, 1994
       https://doi.org/10.3892/or.1.6.1207
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Abstract

Herpes simplex virus (HSV), cytomegalovirus (CMV) and Epstein-Barr virus (EBV) have been recognized as pathogenic agents of intraocular inflammatory conditions. The ability of the Polymerase Chain Reaction (PCR) technique to amplify HSV, CMV and EBV DNA from aqueous specimens makes this technique a valuable diagnostic tool for the detection of these viral pathogens in patients with ophthalmic lesions. We used PCR for the amplification of a 476 bp long sequence from the pol I gene of HSV genome, a 435 bp region of the immediate early-1 (IE-1) gene of CMV and a 375 bp sequence from the EcoRI B fragment of EBV genome. We examined 22 aqueous humour specimens from patients with uveitis and retinitis, inflammatory eye diseases, diagnosed clinically. We found HSV in 4 (18.2%), CMV in 6 (27.3%) and EBV in 1 (4.5%) out of the 22 examined patients. None of the 22 examined samples was found to be infected with more than one of the examined viral pathogens. These data confirm the implications of the members of Herpesvirus family in inflammatory inner eye diseases and the importance of PCR technique as a diagnostic tool in clinical virology.

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Copy and paste a formatted citation
Spandidos Publications style
ERGAZAKI M, XINARIANOS G, GIANNOUDIS A, MARKOMICHELAKIS N, TSAMPARLAKIS J and SPANDIDOS D: DETECTION OF HSV, CMV AND EBV BY THE POLYMERASE CHAIN-REACTION TECHNIQUE IN PATIENTS WITH INFLAMMATORY EYE-DISEASES. Oncol Rep 1: 1207-1210, 1994.
APA
ERGAZAKI, M., XINARIANOS, G., GIANNOUDIS, A., MARKOMICHELAKIS, N., TSAMPARLAKIS, J., & SPANDIDOS, D. (1994). DETECTION OF HSV, CMV AND EBV BY THE POLYMERASE CHAIN-REACTION TECHNIQUE IN PATIENTS WITH INFLAMMATORY EYE-DISEASES. Oncology Reports, 1, 1207-1210. https://doi.org/10.3892/or.1.6.1207
MLA
ERGAZAKI, M., XINARIANOS, G., GIANNOUDIS, A., MARKOMICHELAKIS, N., TSAMPARLAKIS, J., SPANDIDOS, D."DETECTION OF HSV, CMV AND EBV BY THE POLYMERASE CHAIN-REACTION TECHNIQUE IN PATIENTS WITH INFLAMMATORY EYE-DISEASES". Oncology Reports 1.6 (1994): 1207-1210.
Chicago
ERGAZAKI, M., XINARIANOS, G., GIANNOUDIS, A., MARKOMICHELAKIS, N., TSAMPARLAKIS, J., SPANDIDOS, D."DETECTION OF HSV, CMV AND EBV BY THE POLYMERASE CHAIN-REACTION TECHNIQUE IN PATIENTS WITH INFLAMMATORY EYE-DISEASES". Oncology Reports 1, no. 6 (1994): 1207-1210. https://doi.org/10.3892/or.1.6.1207
Copy and paste a formatted citation
x
Spandidos Publications style
ERGAZAKI M, XINARIANOS G, GIANNOUDIS A, MARKOMICHELAKIS N, TSAMPARLAKIS J and SPANDIDOS D: DETECTION OF HSV, CMV AND EBV BY THE POLYMERASE CHAIN-REACTION TECHNIQUE IN PATIENTS WITH INFLAMMATORY EYE-DISEASES. Oncol Rep 1: 1207-1210, 1994.
APA
ERGAZAKI, M., XINARIANOS, G., GIANNOUDIS, A., MARKOMICHELAKIS, N., TSAMPARLAKIS, J., & SPANDIDOS, D. (1994). DETECTION OF HSV, CMV AND EBV BY THE POLYMERASE CHAIN-REACTION TECHNIQUE IN PATIENTS WITH INFLAMMATORY EYE-DISEASES. Oncology Reports, 1, 1207-1210. https://doi.org/10.3892/or.1.6.1207
MLA
ERGAZAKI, M., XINARIANOS, G., GIANNOUDIS, A., MARKOMICHELAKIS, N., TSAMPARLAKIS, J., SPANDIDOS, D."DETECTION OF HSV, CMV AND EBV BY THE POLYMERASE CHAIN-REACTION TECHNIQUE IN PATIENTS WITH INFLAMMATORY EYE-DISEASES". Oncology Reports 1.6 (1994): 1207-1210.
Chicago
ERGAZAKI, M., XINARIANOS, G., GIANNOUDIS, A., MARKOMICHELAKIS, N., TSAMPARLAKIS, J., SPANDIDOS, D."DETECTION OF HSV, CMV AND EBV BY THE POLYMERASE CHAIN-REACTION TECHNIQUE IN PATIENTS WITH INFLAMMATORY EYE-DISEASES". Oncology Reports 1, no. 6 (1994): 1207-1210. https://doi.org/10.3892/or.1.6.1207
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