Apoptosis: Escaping strategies in human skin cancer (Review)

  • Authors:
    • Luca Giannetti
    • Ugo Consolo
    • Cristina Magnoni
    • Lorenzo Lo Muzio
  • View Affiliations

  • Published online on: February 1, 2004     https://doi.org/10.3892/or.11.2.401
  • Pages: 401-405
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Abstract

Apoptosis must be considered a rescue mechanism that controls the integrity of the cell erasing aberrant clones and it is likely that failure of apoptosis constitutes a key factor responsible for tumour formation, progression and resistance to drugs. Several genes (e.g. survivin, bcl-2 family, p53) are involved in these pathways. Much work still needs to be done to identify the molecular pathway of apoptosis resistance but restoration of the apoptotic response represents a crucial new therapeutic target for cancer treatment.

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February 2004
Volume 11 Issue 2

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Giannetti L, Consolo U, Magnoni C and Lo Muzio L: Apoptosis: Escaping strategies in human skin cancer (Review). Oncol Rep 11: 401-405, 2004
APA
Giannetti, L., Consolo, U., Magnoni, C., & Lo Muzio, L. (2004). Apoptosis: Escaping strategies in human skin cancer (Review). Oncology Reports, 11, 401-405. https://doi.org/10.3892/or.11.2.401
MLA
Giannetti, L., Consolo, U., Magnoni, C., Lo Muzio, L."Apoptosis: Escaping strategies in human skin cancer (Review)". Oncology Reports 11.2 (2004): 401-405.
Chicago
Giannetti, L., Consolo, U., Magnoni, C., Lo Muzio, L."Apoptosis: Escaping strategies in human skin cancer (Review)". Oncology Reports 11, no. 2 (2004): 401-405. https://doi.org/10.3892/or.11.2.401