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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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September 2005 Volume 14 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Article

Response to radiotherapy in brain metastases and survival of patients with non-small cell lung cancer

  • Authors:
    • Dimosthenis Antoniou
    • Kostas Kyprianou
    • George P. Stathopoulos
    • Christos Skarleas
    • Georgia Kolitsi
    • Marinos Veslemes
    • John Dimitroulis
    • Pantelis Giamboudakis
    • Kostas Marosis
    • Ourania Armenaki
    • C. Papageorgiou
    • Costas Katis

  • View Affiliations / Copyright

    Affiliations: Hospital of Thoracic Diseases, Athens, Greece
  • Pages: 733-736
    |
    Published online on: September 1, 2005
       https://doi.org/10.3892/or.14.3.733
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Abstract

The present study involves non-small cell lung (NSCLC) cancer patients with brain metastases, who were treated with radiation therapy, and our aim was to determine response rate and survival. A total of 167 patients were recruited, 155 (125 male, 30 female) of whom were evaluable. Performance status was 0-2 and histology or cytology included 66 (42.58%) adenocarcinomas, 62 (40.00%) undifferentiated and 27 (17.42%) squamous cell carcinomas. The stage of disease at diagnosis was IIIA-B in 92 (59.35%) patients and IV in 63 (40.65%). All patients had whole brain irradiation (3 Gy x5 days/week for 2 weeks to a total dose of 30 Gy), which was performed by a linear accelerator and a 6-MV photon beam. Objective response was observed in 59/155 (38.06%) patients with 17 (10.97%) complete and 42 (27.09%) partial responses, and median survival of 5 months for all patients [95% confidence interval (CI) 3.9-6.1]. Responders had statistically significant longer survival than non-responders. Although responders represented less than half of our patients with NSCLC and brain metastases, they had significantly longer survival.

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Copy and paste a formatted citation
Spandidos Publications style
Antoniou D, Kyprianou K, Stathopoulos GP, Skarleas C, Kolitsi G, Veslemes M, Dimitroulis J, Giamboudakis P, Marosis K, Armenaki O, Armenaki O, et al: Response to radiotherapy in brain metastases and survival of patients with non-small cell lung cancer. Oncol Rep 14: 733-736, 2005.
APA
Antoniou, D., Kyprianou, K., Stathopoulos, G.P., Skarleas, C., Kolitsi, G., Veslemes, M. ... Katis, C. (2005). Response to radiotherapy in brain metastases and survival of patients with non-small cell lung cancer. Oncology Reports, 14, 733-736. https://doi.org/10.3892/or.14.3.733
MLA
Antoniou, D., Kyprianou, K., Stathopoulos, G. P., Skarleas, C., Kolitsi, G., Veslemes, M., Dimitroulis, J., Giamboudakis, P., Marosis, K., Armenaki, O., Papageorgiou, C., Katis, C."Response to radiotherapy in brain metastases and survival of patients with non-small cell lung cancer". Oncology Reports 14.3 (2005): 733-736.
Chicago
Antoniou, D., Kyprianou, K., Stathopoulos, G. P., Skarleas, C., Kolitsi, G., Veslemes, M., Dimitroulis, J., Giamboudakis, P., Marosis, K., Armenaki, O., Papageorgiou, C., Katis, C."Response to radiotherapy in brain metastases and survival of patients with non-small cell lung cancer". Oncology Reports 14, no. 3 (2005): 733-736. https://doi.org/10.3892/or.14.3.733
Copy and paste a formatted citation
x
Spandidos Publications style
Antoniou D, Kyprianou K, Stathopoulos GP, Skarleas C, Kolitsi G, Veslemes M, Dimitroulis J, Giamboudakis P, Marosis K, Armenaki O, Armenaki O, et al: Response to radiotherapy in brain metastases and survival of patients with non-small cell lung cancer. Oncol Rep 14: 733-736, 2005.
APA
Antoniou, D., Kyprianou, K., Stathopoulos, G.P., Skarleas, C., Kolitsi, G., Veslemes, M. ... Katis, C. (2005). Response to radiotherapy in brain metastases and survival of patients with non-small cell lung cancer. Oncology Reports, 14, 733-736. https://doi.org/10.3892/or.14.3.733
MLA
Antoniou, D., Kyprianou, K., Stathopoulos, G. P., Skarleas, C., Kolitsi, G., Veslemes, M., Dimitroulis, J., Giamboudakis, P., Marosis, K., Armenaki, O., Papageorgiou, C., Katis, C."Response to radiotherapy in brain metastases and survival of patients with non-small cell lung cancer". Oncology Reports 14.3 (2005): 733-736.
Chicago
Antoniou, D., Kyprianou, K., Stathopoulos, G. P., Skarleas, C., Kolitsi, G., Veslemes, M., Dimitroulis, J., Giamboudakis, P., Marosis, K., Armenaki, O., Papageorgiou, C., Katis, C."Response to radiotherapy in brain metastases and survival of patients with non-small cell lung cancer". Oncology Reports 14, no. 3 (2005): 733-736. https://doi.org/10.3892/or.14.3.733
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