In the present study, we experimentally examined the feasibility of two-colonoscope surgery using two types of forceps to achieve safe, reliable, and complete endoscopic mucosal resection (EMR)/endoscopic submucosal dissection (ESD) of large superficial tumors in the right colon. It was confirmed at all experimental sessions that the two pairs of forceps intersected with each other over a wide angle of at least 90° in the cecum, and that the tips of the forceps could be moved by at least 180° in the longitudinal and horizontal directions. In another experiment, a piece of tissue measuring 3x3 cm or larger could be safely resected from a chicken thigh as the pseudo-tumor. Based on these results, two-colonoscope surgery is considered clinically promising as a next-generation EMR/ESD technique for safe, reliable, and complete resection of superficial tumors of the right colon measuring 3 cm or more in diameter.

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