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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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May 1995 Volume 2 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Medicine International

An International Open Access Journal Devoted to General Medicine.

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May 1995 Volume 2 Issue 3

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Article

STRAIN DIFFERENCES IN MOUSE SKIN TUMORIGENESIS BY THE PROMOTION OF 12-O-TETRADECANOYLPHORBOL-13-ACETATE OR BENZOYL PEROXIDE

  • Authors:
    • PO OGUNDIGIE
    • H WATANABE
    • K YAMADA
    • A ITO

  • View Affiliations / Copyright

    Affiliations: HIROSHIMA UNIV,RADIAT BIOL & MED RES INST,DIV CANC RES,MINAMI KU,HIROSHIMA 734,JAPAN.
  • Pages: 369-375
    |
    Published online on: May 1, 1995
       https://doi.org/10.3892/or.2.3.369
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Abstract

Strain difference of mouse skin tumorigenesis was studied with 12-O-tetradecanoylphorbol-13-acetate (TPA) and benzoyl peroxide (BzP) both in 8-week-old hypocatalasemic C3H mice (C-s(b)) and in normal C3H/HeNCrj mice (C3H). Two weeks after initiation by 4 mu mole MNNG, both strains of female mice were promoted by 10 nmole TPA or 10 mg, 20 mg BzP twice weekly for 30 and 52 weeks. The incidence of skin tumors in C-b(s) was significantly increased as compared to that in C3H mice promoted by TPA for 30 weeks but after 52 weeks of TPA promotion there was no difference between the 2 strains. By the promotion with 10 mg or 20 mg BzP, the incidence of skin tumor in C3H was 5% at both levels after 30 weeks of promotion and 19% and 38%, respectively, after 52 weeks of promotion. No skin tumors appeared in C-b(s) mice with BzP treatment after 30 weeks of promotion. After 52 weeks of promotion by 10 mg BzP, skin tumors were induced in only 15% of C-b(s) mice. The results show that genetic factors, especially radical scavenging enzymes, controlled susceptibility to skin tumorigenesis by promotion with either TPA or BzP.

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Copy and paste a formatted citation
Spandidos Publications style
OGUNDIGIE P, WATANABE H, YAMADA K and ITO A: STRAIN DIFFERENCES IN MOUSE SKIN TUMORIGENESIS BY THE PROMOTION OF 12-O-TETRADECANOYLPHORBOL-13-ACETATE OR BENZOYL PEROXIDE. Oncol Rep 2: 369-375, 1995.
APA
OGUNDIGIE, P., WATANABE, H., YAMADA, K., & ITO, A. (1995). STRAIN DIFFERENCES IN MOUSE SKIN TUMORIGENESIS BY THE PROMOTION OF 12-O-TETRADECANOYLPHORBOL-13-ACETATE OR BENZOYL PEROXIDE. Oncology Reports, 2, 369-375. https://doi.org/10.3892/or.2.3.369
MLA
OGUNDIGIE, P., WATANABE, H., YAMADA, K., ITO, A."STRAIN DIFFERENCES IN MOUSE SKIN TUMORIGENESIS BY THE PROMOTION OF 12-O-TETRADECANOYLPHORBOL-13-ACETATE OR BENZOYL PEROXIDE". Oncology Reports 2.3 (1995): 369-375.
Chicago
OGUNDIGIE, P., WATANABE, H., YAMADA, K., ITO, A."STRAIN DIFFERENCES IN MOUSE SKIN TUMORIGENESIS BY THE PROMOTION OF 12-O-TETRADECANOYLPHORBOL-13-ACETATE OR BENZOYL PEROXIDE". Oncology Reports 2, no. 3 (1995): 369-375. https://doi.org/10.3892/or.2.3.369
Copy and paste a formatted citation
x
Spandidos Publications style
OGUNDIGIE P, WATANABE H, YAMADA K and ITO A: STRAIN DIFFERENCES IN MOUSE SKIN TUMORIGENESIS BY THE PROMOTION OF 12-O-TETRADECANOYLPHORBOL-13-ACETATE OR BENZOYL PEROXIDE. Oncol Rep 2: 369-375, 1995.
APA
OGUNDIGIE, P., WATANABE, H., YAMADA, K., & ITO, A. (1995). STRAIN DIFFERENCES IN MOUSE SKIN TUMORIGENESIS BY THE PROMOTION OF 12-O-TETRADECANOYLPHORBOL-13-ACETATE OR BENZOYL PEROXIDE. Oncology Reports, 2, 369-375. https://doi.org/10.3892/or.2.3.369
MLA
OGUNDIGIE, P., WATANABE, H., YAMADA, K., ITO, A."STRAIN DIFFERENCES IN MOUSE SKIN TUMORIGENESIS BY THE PROMOTION OF 12-O-TETRADECANOYLPHORBOL-13-ACETATE OR BENZOYL PEROXIDE". Oncology Reports 2.3 (1995): 369-375.
Chicago
OGUNDIGIE, P., WATANABE, H., YAMADA, K., ITO, A."STRAIN DIFFERENCES IN MOUSE SKIN TUMORIGENESIS BY THE PROMOTION OF 12-O-TETRADECANOYLPHORBOL-13-ACETATE OR BENZOYL PEROXIDE". Oncology Reports 2, no. 3 (1995): 369-375. https://doi.org/10.3892/or.2.3.369
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