BILATERAL RENAL-CELL CARCINOMA OF THE NATIVE KIDNEYS AFTER RENAL-TRANSPLANTATION

  • Authors:
    • M CARMELLINI
    • J ROMAGNOLI
    • G RIZZO
    • A MARCHETTI
    • F MOSCA
  • View Affiliations

  • Published online on: May 1, 1995     https://doi.org/10.3892/or.2.3.435
  • Pages: 435-437
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Abstract

We report the case of a 45-year-old man who received a cadaveric renal transplant and subsequently developed a bilateral neoplasm of the native kidneys. Two tumors per each kidney were detected and in the left kidney they were cytologically different, one granular and one clear cell type. Bilateral nephrectomy with radical lymphadenectomy was performed, immunosuppression was withdrawn and medrossiprogesterone was administered. A control CT scan 3 months after surgery demonstrated no evidence of neoplastic recurrence, while ultrasonography detected a liver metastasis. The patient subsequently developed a para-neoplastic syndrome and died 7 months after surgery. We believe that all long-term immunosuppressed transplant patients need close observation. Regular imaging of the native kidneys, by ultrasound or CT, should be carried out yearly. Prophylactic bilateral nephrectomy is not desirable because of the loss of the important mechanism of pressure control. mediated by the renine-angiotensin system.

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May 1995
Volume 2 Issue 3

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
CARMELLINI M, ROMAGNOLI J, RIZZO G, MARCHETTI A and MOSCA F: BILATERAL RENAL-CELL CARCINOMA OF THE NATIVE KIDNEYS AFTER RENAL-TRANSPLANTATION. Oncol Rep 2: 435-437, 1995
APA
CARMELLINI, M., ROMAGNOLI, J., RIZZO, G., MARCHETTI, A., & MOSCA, F. (1995). BILATERAL RENAL-CELL CARCINOMA OF THE NATIVE KIDNEYS AFTER RENAL-TRANSPLANTATION. Oncology Reports, 2, 435-437. https://doi.org/10.3892/or.2.3.435
MLA
CARMELLINI, M., ROMAGNOLI, J., RIZZO, G., MARCHETTI, A., MOSCA, F."BILATERAL RENAL-CELL CARCINOMA OF THE NATIVE KIDNEYS AFTER RENAL-TRANSPLANTATION". Oncology Reports 2.3 (1995): 435-437.
Chicago
CARMELLINI, M., ROMAGNOLI, J., RIZZO, G., MARCHETTI, A., MOSCA, F."BILATERAL RENAL-CELL CARCINOMA OF THE NATIVE KIDNEYS AFTER RENAL-TRANSPLANTATION". Oncology Reports 2, no. 3 (1995): 435-437. https://doi.org/10.3892/or.2.3.435