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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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May 1995 Volume 2 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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May 1995 Volume 2 Issue 3

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Article

CULTURED CHINESE-HAMSTER OVARY CELLS LACK A TRANSFERABLE X-RADIATION RESISTANCE FACTOR

  • Authors:
    • CE NG
    • DP YANG
    • AM BUSSEY
    • GP RAAPHORST

  • View Affiliations / Copyright

    Affiliations: Affliations not specified
  • Pages: 439-442
    |
    Published online on: May 1, 1995
       https://doi.org/10.3892/or.2.3.439
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Abstract

We determined if we could transfer X-radiation resistance from CHO AA8 cells to their radiosensitive, mutant V3 cells by several methods. These methods include co-incubating the two cell lines for three days before irradiation, adding heavily-irradiated AA8 to V3 cells following irradiation of the latter and then co-incubating these cells for at least eight days during the colony-forming assay and lastly, adding conditioned medium from unirradiated, subconfluent AA8 cells to V3 cultures and incubating for two days before irradiation. None of these procedures enhanced the clonogenic survival of the V3 cells to a single dose of 4 Gy X-radiation. Adding heavily-irradiated V3, instead of AA8, cells did not increase the clonogenic survival of the 4 Gy-irradiated V3 cells either, indicating that there was no autocrine mode of action. Moreover, adding conditioned medium from a related CHO cell line, K1, to its own radiosensitive, mutant 5-11 and incubating for two days before irradiation did not enhance clonogenic survival of the latter to a single dose of 3 Gy X-radiation. We therefore conclude that it is unlikely that CHO cells have the X-radiation resistance factor that has been reported in some mouse melanoma cell lines by other investigators.

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Copy and paste a formatted citation
Spandidos Publications style
NG C, YANG D, BUSSEY A and RAAPHORST G: CULTURED CHINESE-HAMSTER OVARY CELLS LACK A TRANSFERABLE X-RADIATION RESISTANCE FACTOR. Oncol Rep 2: 439-442, 1995.
APA
NG, C., YANG, D., BUSSEY, A., & RAAPHORST, G. (1995). CULTURED CHINESE-HAMSTER OVARY CELLS LACK A TRANSFERABLE X-RADIATION RESISTANCE FACTOR. Oncology Reports, 2, 439-442. https://doi.org/10.3892/or.2.3.439
MLA
NG, C., YANG, D., BUSSEY, A., RAAPHORST, G."CULTURED CHINESE-HAMSTER OVARY CELLS LACK A TRANSFERABLE X-RADIATION RESISTANCE FACTOR". Oncology Reports 2.3 (1995): 439-442.
Chicago
NG, C., YANG, D., BUSSEY, A., RAAPHORST, G."CULTURED CHINESE-HAMSTER OVARY CELLS LACK A TRANSFERABLE X-RADIATION RESISTANCE FACTOR". Oncology Reports 2, no. 3 (1995): 439-442. https://doi.org/10.3892/or.2.3.439
Copy and paste a formatted citation
x
Spandidos Publications style
NG C, YANG D, BUSSEY A and RAAPHORST G: CULTURED CHINESE-HAMSTER OVARY CELLS LACK A TRANSFERABLE X-RADIATION RESISTANCE FACTOR. Oncol Rep 2: 439-442, 1995.
APA
NG, C., YANG, D., BUSSEY, A., & RAAPHORST, G. (1995). CULTURED CHINESE-HAMSTER OVARY CELLS LACK A TRANSFERABLE X-RADIATION RESISTANCE FACTOR. Oncology Reports, 2, 439-442. https://doi.org/10.3892/or.2.3.439
MLA
NG, C., YANG, D., BUSSEY, A., RAAPHORST, G."CULTURED CHINESE-HAMSTER OVARY CELLS LACK A TRANSFERABLE X-RADIATION RESISTANCE FACTOR". Oncology Reports 2.3 (1995): 439-442.
Chicago
NG, C., YANG, D., BUSSEY, A., RAAPHORST, G."CULTURED CHINESE-HAMSTER OVARY CELLS LACK A TRANSFERABLE X-RADIATION RESISTANCE FACTOR". Oncology Reports 2, no. 3 (1995): 439-442. https://doi.org/10.3892/or.2.3.439
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