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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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July 1995 Volume 2 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July 1995 Volume 2 Issue 4

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POSITRON EMISSION TOMOGRAPHY UTILIZING C-11 5-HYDROXYTRYPTOPHAN, PLASMA BIOCHEMISTRY AND NEUROENDOCRINE IMMUNOHISTOCHEMISTRY OF METASTATIC RENAL-CELL CARCINOMA

  • Authors:
    • JE WESTLIN
    • M EDGREN
    • H LETOCHA
    • M STRIDSBERG
    • E WILANDER
    • S NILSSON

  • View Affiliations / Copyright

    Affiliations: UNIV UPPSALA HOSP,DEPT CLIN CHEM,S-75185 UPPSALA,SWEDEN. UNIV UPPSALA HOSP,DEPT PATHOL,S-75185 UPPSALA,SWEDEN. UPPSALA UNIV,PET CTR,UPPSALA,SWEDEN.
  • Pages: 543-548
    |
    Published online on: July 1, 1995
       https://doi.org/10.3892/or.2.4.543
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Abstract

The aim of this study was to characterise metastatic renal cell carcinoma in 18 patients with positron emission tomography (PET) utilising C-11-5-hydroxytryptophan, plasma biochemistry and neuroendocrine immunochemistry. Of these 18 patients, ten underwent the PET investigations. The standardised uptake values (SUVs) in hepatic deposits were higher than those in pulmonary lesions, with mean values of 3.15 and 2.35, respectively. The immunohistochemical study included staining of 10/18 surgical tumour specimens with antibodies reactive with chromogranin (Cg), neurone-specific enolase (NSE), and synaptophysin (Sy). In 17/18 patients, plasma measurements of the neuroendocrine peptides, CgA, CgB, pancreastatin, and serotonin, were performed. The results obtained in this study show that PET with C-11-5-hydroxytryptophan, a precursor in serotonin synthesis in neuroendocrine cells, can be utilised to visualise primary renal cell cancer and its secondaries in vivo. The results obtained also suggest that neuroendocrine differentiation may occur in human RCC.

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Copy and paste a formatted citation
Spandidos Publications style
WESTLIN J, EDGREN M, LETOCHA H, STRIDSBERG M, WILANDER E and NILSSON S: POSITRON EMISSION TOMOGRAPHY UTILIZING C-11 5-HYDROXYTRYPTOPHAN, PLASMA BIOCHEMISTRY AND NEUROENDOCRINE IMMUNOHISTOCHEMISTRY OF METASTATIC RENAL-CELL CARCINOMA. Oncol Rep 2: 543-548, 1995.
APA
WESTLIN, J., EDGREN, M., LETOCHA, H., STRIDSBERG, M., WILANDER, E., & NILSSON, S. (1995). POSITRON EMISSION TOMOGRAPHY UTILIZING C-11 5-HYDROXYTRYPTOPHAN, PLASMA BIOCHEMISTRY AND NEUROENDOCRINE IMMUNOHISTOCHEMISTRY OF METASTATIC RENAL-CELL CARCINOMA. Oncology Reports, 2, 543-548. https://doi.org/10.3892/or.2.4.543
MLA
WESTLIN, J., EDGREN, M., LETOCHA, H., STRIDSBERG, M., WILANDER, E., NILSSON, S."POSITRON EMISSION TOMOGRAPHY UTILIZING C-11 5-HYDROXYTRYPTOPHAN, PLASMA BIOCHEMISTRY AND NEUROENDOCRINE IMMUNOHISTOCHEMISTRY OF METASTATIC RENAL-CELL CARCINOMA". Oncology Reports 2.4 (1995): 543-548.
Chicago
WESTLIN, J., EDGREN, M., LETOCHA, H., STRIDSBERG, M., WILANDER, E., NILSSON, S."POSITRON EMISSION TOMOGRAPHY UTILIZING C-11 5-HYDROXYTRYPTOPHAN, PLASMA BIOCHEMISTRY AND NEUROENDOCRINE IMMUNOHISTOCHEMISTRY OF METASTATIC RENAL-CELL CARCINOMA". Oncology Reports 2, no. 4 (1995): 543-548. https://doi.org/10.3892/or.2.4.543
Copy and paste a formatted citation
x
Spandidos Publications style
WESTLIN J, EDGREN M, LETOCHA H, STRIDSBERG M, WILANDER E and NILSSON S: POSITRON EMISSION TOMOGRAPHY UTILIZING C-11 5-HYDROXYTRYPTOPHAN, PLASMA BIOCHEMISTRY AND NEUROENDOCRINE IMMUNOHISTOCHEMISTRY OF METASTATIC RENAL-CELL CARCINOMA. Oncol Rep 2: 543-548, 1995.
APA
WESTLIN, J., EDGREN, M., LETOCHA, H., STRIDSBERG, M., WILANDER, E., & NILSSON, S. (1995). POSITRON EMISSION TOMOGRAPHY UTILIZING C-11 5-HYDROXYTRYPTOPHAN, PLASMA BIOCHEMISTRY AND NEUROENDOCRINE IMMUNOHISTOCHEMISTRY OF METASTATIC RENAL-CELL CARCINOMA. Oncology Reports, 2, 543-548. https://doi.org/10.3892/or.2.4.543
MLA
WESTLIN, J., EDGREN, M., LETOCHA, H., STRIDSBERG, M., WILANDER, E., NILSSON, S."POSITRON EMISSION TOMOGRAPHY UTILIZING C-11 5-HYDROXYTRYPTOPHAN, PLASMA BIOCHEMISTRY AND NEUROENDOCRINE IMMUNOHISTOCHEMISTRY OF METASTATIC RENAL-CELL CARCINOMA". Oncology Reports 2.4 (1995): 543-548.
Chicago
WESTLIN, J., EDGREN, M., LETOCHA, H., STRIDSBERG, M., WILANDER, E., NILSSON, S."POSITRON EMISSION TOMOGRAPHY UTILIZING C-11 5-HYDROXYTRYPTOPHAN, PLASMA BIOCHEMISTRY AND NEUROENDOCRINE IMMUNOHISTOCHEMISTRY OF METASTATIC RENAL-CELL CARCINOMA". Oncology Reports 2, no. 4 (1995): 543-548. https://doi.org/10.3892/or.2.4.543
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