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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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July 1995 Volume 2 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July 1995 Volume 2 Issue 4

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Article

TISSUE POLYPEPTIDE ANTIGEN-SPECIFIC (TPS) AND CARCINOEMBRYONIC ANTIGEN (CEA) LEVELS IN CANCEROUS AND PRECANCEROUS LESIONS IN HUMAN COLON

  • Authors:
    • B SLESAK
    • A HARLOZINSKASZMYRKA
    • A VANDALEN
    • P SEDLACZEK
    • J LAPINSKA
    • R EINARSSON

  • View Affiliations / Copyright

    Affiliations: WROCLAW UNIV MED,GASTROENTEROL CLIN,PL-50368 WROCLAW,POLAND. GROENE HART ZIEKENHUIS,DEPT NUCL MED,GOUDA,NETHERLANDS. BEKI DIAGNOST AB,STOCKHOLM,SWEDEN.
  • Pages: 567-570
    |
    Published online on: July 1, 1995
       https://doi.org/10.3892/or.2.4.567
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Abstract

Serum levels of tissue polypeptide antigen specific (TPS), a cytokeratin 18 marker, were determined and compared with serum levels of carcinoembryonic antigen (CEA) in 45 patients with colon adenocarcinoma and in 34 patients with benign diseases (adenomatous polyps and ulcerative colitis) at the time of diagnosis. In colon carcinoma patients 58% had an elevated TPS level (cut-off 100 U/l) and 53% had an elevated CEA level (cut-off 3.0 ng/ml). The sensitivity of the cytokeratin marker TPS was related to the stage of the disease. Significant correlation was observed between TPS and Dukes stages in colon cancer patients and the highest TPS values were achieved in Dukes stage D. The combined use of the two markers increased the sensitivity to 82% compared with the use of only one. Simultaneous raise of both serum markers TPS and CEA was observed in 36% of cases. In the majority of the patients with adenomatous polyps and ulcerative colitis the serum TPS and CEA levels were below the upper reference limit. However the initial high levels in some patients could be considered as a prognostic indicator for identifying a group of patients with increased risk of cancer development. No significant correlation was observed between serum TPS and CEA concentrations in individual patients with benign diseases.

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Copy and paste a formatted citation
Spandidos Publications style
SLESAK B, HARLOZINSKASZMYRKA A, VANDALEN A, SEDLACZEK P, LAPINSKA J and EINARSSON R: TISSUE POLYPEPTIDE ANTIGEN-SPECIFIC (TPS) AND CARCINOEMBRYONIC ANTIGEN (CEA) LEVELS IN CANCEROUS AND PRECANCEROUS LESIONS IN HUMAN COLON. Oncol Rep 2: 567-570, 1995.
APA
SLESAK, B., HARLOZINSKASZMYRKA, A., VANDALEN, A., SEDLACZEK, P., LAPINSKA, J., & EINARSSON, R. (1995). TISSUE POLYPEPTIDE ANTIGEN-SPECIFIC (TPS) AND CARCINOEMBRYONIC ANTIGEN (CEA) LEVELS IN CANCEROUS AND PRECANCEROUS LESIONS IN HUMAN COLON. Oncology Reports, 2, 567-570. https://doi.org/10.3892/or.2.4.567
MLA
SLESAK, B., HARLOZINSKASZMYRKA, A., VANDALEN, A., SEDLACZEK, P., LAPINSKA, J., EINARSSON, R."TISSUE POLYPEPTIDE ANTIGEN-SPECIFIC (TPS) AND CARCINOEMBRYONIC ANTIGEN (CEA) LEVELS IN CANCEROUS AND PRECANCEROUS LESIONS IN HUMAN COLON". Oncology Reports 2.4 (1995): 567-570.
Chicago
SLESAK, B., HARLOZINSKASZMYRKA, A., VANDALEN, A., SEDLACZEK, P., LAPINSKA, J., EINARSSON, R."TISSUE POLYPEPTIDE ANTIGEN-SPECIFIC (TPS) AND CARCINOEMBRYONIC ANTIGEN (CEA) LEVELS IN CANCEROUS AND PRECANCEROUS LESIONS IN HUMAN COLON". Oncology Reports 2, no. 4 (1995): 567-570. https://doi.org/10.3892/or.2.4.567
Copy and paste a formatted citation
x
Spandidos Publications style
SLESAK B, HARLOZINSKASZMYRKA A, VANDALEN A, SEDLACZEK P, LAPINSKA J and EINARSSON R: TISSUE POLYPEPTIDE ANTIGEN-SPECIFIC (TPS) AND CARCINOEMBRYONIC ANTIGEN (CEA) LEVELS IN CANCEROUS AND PRECANCEROUS LESIONS IN HUMAN COLON. Oncol Rep 2: 567-570, 1995.
APA
SLESAK, B., HARLOZINSKASZMYRKA, A., VANDALEN, A., SEDLACZEK, P., LAPINSKA, J., & EINARSSON, R. (1995). TISSUE POLYPEPTIDE ANTIGEN-SPECIFIC (TPS) AND CARCINOEMBRYONIC ANTIGEN (CEA) LEVELS IN CANCEROUS AND PRECANCEROUS LESIONS IN HUMAN COLON. Oncology Reports, 2, 567-570. https://doi.org/10.3892/or.2.4.567
MLA
SLESAK, B., HARLOZINSKASZMYRKA, A., VANDALEN, A., SEDLACZEK, P., LAPINSKA, J., EINARSSON, R."TISSUE POLYPEPTIDE ANTIGEN-SPECIFIC (TPS) AND CARCINOEMBRYONIC ANTIGEN (CEA) LEVELS IN CANCEROUS AND PRECANCEROUS LESIONS IN HUMAN COLON". Oncology Reports 2.4 (1995): 567-570.
Chicago
SLESAK, B., HARLOZINSKASZMYRKA, A., VANDALEN, A., SEDLACZEK, P., LAPINSKA, J., EINARSSON, R."TISSUE POLYPEPTIDE ANTIGEN-SPECIFIC (TPS) AND CARCINOEMBRYONIC ANTIGEN (CEA) LEVELS IN CANCEROUS AND PRECANCEROUS LESIONS IN HUMAN COLON". Oncology Reports 2, no. 4 (1995): 567-570. https://doi.org/10.3892/or.2.4.567
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