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GONADOTROPIN-RELEASING-HORMONE (GN-RH) RECEPTOR IN THE REPRODUCTIVE-TRACT TUMOR - PHYSIOLOGICAL-ROLE AND SIGNAL-TRANSDUCTION PATHWAY

  • Authors:
    • A IMAI
    • S HORIBE
    • H TAKAGI
    • T FUSEYA
    • T FURUI
    • T TAMAYA

  • View Affiliations

  • Published online on: July 1, 1995     https://doi.org/10.3892/or.2.4.625
  • Pages: 625-631
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Abstract

Gonadotropin-releasing hormoen (Gn-RH) analogs have been used in the therapy of the endocrine-dependent cancers including the repductive tract-originated tumors. Gn-RH receptor and its transmembrane signaling pathways have been demonstrated in a high proportion of these tumors. The demonstration of existence of receptors for a hormone can better predict hormonal dependency, and might be a first step towards an effective hormonal treatment. These findings suggest the merit of further therapeutic investigations of Gn-RH analogs alone or in combination with traditional therapies in the management of Gn-RH receptor-positive tumors.

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Journal Cover

July 1995
Volume 2 Issue 4

Print ISSN: 1021-335X
Online ISSN:1791-2431

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  • Journal Metrics
  • Impact Factor: 4.2
  • Ranked Oncology
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  • CiteScore: 8.4
  • CiteScore Rank: Q1: #68/366 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.786
  • SCImago Journal Rank (SJR): 0.812
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Spandidos Publications style
IMAI A, HORIBE S, TAKAGI H, FUSEYA T, FURUI T and TAMAYA T: GONADOTROPIN-RELEASING-HORMONE (GN-RH) RECEPTOR IN THE REPRODUCTIVE-TRACT TUMOR - PHYSIOLOGICAL-ROLE AND SIGNAL-TRANSDUCTION PATHWAY. Oncol Rep 2: 625-631, 1995
APA
IMAI, A., HORIBE, S., TAKAGI, H., FUSEYA, T., FURUI, T., & TAMAYA, T. (1995). GONADOTROPIN-RELEASING-HORMONE (GN-RH) RECEPTOR IN THE REPRODUCTIVE-TRACT TUMOR - PHYSIOLOGICAL-ROLE AND SIGNAL-TRANSDUCTION PATHWAY. Oncology Reports, 2, 625-631. https://doi.org/10.3892/or.2.4.625
MLA
IMAI, A., HORIBE, S., TAKAGI, H., FUSEYA, T., FURUI, T., TAMAYA, T."GONADOTROPIN-RELEASING-HORMONE (GN-RH) RECEPTOR IN THE REPRODUCTIVE-TRACT TUMOR - PHYSIOLOGICAL-ROLE AND SIGNAL-TRANSDUCTION PATHWAY". Oncology Reports 2.4 (1995): 625-631.
Chicago
IMAI, A., HORIBE, S., TAKAGI, H., FUSEYA, T., FURUI, T., TAMAYA, T."GONADOTROPIN-RELEASING-HORMONE (GN-RH) RECEPTOR IN THE REPRODUCTIVE-TRACT TUMOR - PHYSIOLOGICAL-ROLE AND SIGNAL-TRANSDUCTION PATHWAY". Oncology Reports 2, no. 4 (1995): 625-631. https://doi.org/10.3892/or.2.4.625