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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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November 1995 Volume 2 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November 1995 Volume 2 Issue 6

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Article

STEREOLOGIC ESTIMATION OF NUCLEAR VOLUME IN GLOTTIC SQUAMOUS-CELL CARCINOMA

  • Authors:
    • X XIE
    • TC STENERSEN
    • OPF CLAUSEN
    • M BOYSEN

  • View Affiliations / Copyright

    Affiliations: UNIV OSLO,NATL HOSP,DEPT OTOLARYNGOL,N-0027 OSLO,NORWAY. UNIV OSLO,NATL HOSP,DEPT PATHOL,N-0027 OSLO,NORWAY.
  • Pages: 1049-1054
    |
    Published online on: November 1, 1995
       https://doi.org/10.3892/or.2.6.1049
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Abstract

By means of a newly developed stereologic model, the point sample intercept technique, we estimated the mean nuclear volume (nuclear (V) over bar v) in 106 T1-4 glottic carcinomas. The original formalin fixed, routinely processed H&E stained diagnostic sections were used. The overall average nuclear (V) over bar v was 782 mu m(3). Neither T- nor N-stage revealed significant differences in nuclear (V) over bar v. Patients dying from glottic carcinoma had a higher nuclear (V) over bar v compared to survivors/patients dying from intercurrent diseases, 917 and 713 mu m(3) respectively (p=0.0042). The distribution of nuclear (V) over bar v suggested that a cut-off level of 900 mu m(3) would give a better separation between clinically favourable and poor prognostic cases (p=0.0004). Both T- and N-stage were highly significant in relation to survival by univariate analysis. Multivariate analysis retained only N-stage (p=0.0001) and nuclear (V) over bar v (p=0.0022). Our results suggest that nuclear (V) over bar v is a strong independent prognostic marker in glottic carcinomas.

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Copy and paste a formatted citation
Spandidos Publications style
XIE X, STENERSEN T, CLAUSEN O and BOYSEN M: STEREOLOGIC ESTIMATION OF NUCLEAR VOLUME IN GLOTTIC SQUAMOUS-CELL CARCINOMA. Oncol Rep 2: 1049-1054, 1995.
APA
XIE, X., STENERSEN, T., CLAUSEN, O., & BOYSEN, M. (1995). STEREOLOGIC ESTIMATION OF NUCLEAR VOLUME IN GLOTTIC SQUAMOUS-CELL CARCINOMA. Oncology Reports, 2, 1049-1054. https://doi.org/10.3892/or.2.6.1049
MLA
XIE, X., STENERSEN, T., CLAUSEN, O., BOYSEN, M."STEREOLOGIC ESTIMATION OF NUCLEAR VOLUME IN GLOTTIC SQUAMOUS-CELL CARCINOMA". Oncology Reports 2.6 (1995): 1049-1054.
Chicago
XIE, X., STENERSEN, T., CLAUSEN, O., BOYSEN, M."STEREOLOGIC ESTIMATION OF NUCLEAR VOLUME IN GLOTTIC SQUAMOUS-CELL CARCINOMA". Oncology Reports 2, no. 6 (1995): 1049-1054. https://doi.org/10.3892/or.2.6.1049
Copy and paste a formatted citation
x
Spandidos Publications style
XIE X, STENERSEN T, CLAUSEN O and BOYSEN M: STEREOLOGIC ESTIMATION OF NUCLEAR VOLUME IN GLOTTIC SQUAMOUS-CELL CARCINOMA. Oncol Rep 2: 1049-1054, 1995.
APA
XIE, X., STENERSEN, T., CLAUSEN, O., & BOYSEN, M. (1995). STEREOLOGIC ESTIMATION OF NUCLEAR VOLUME IN GLOTTIC SQUAMOUS-CELL CARCINOMA. Oncology Reports, 2, 1049-1054. https://doi.org/10.3892/or.2.6.1049
MLA
XIE, X., STENERSEN, T., CLAUSEN, O., BOYSEN, M."STEREOLOGIC ESTIMATION OF NUCLEAR VOLUME IN GLOTTIC SQUAMOUS-CELL CARCINOMA". Oncology Reports 2.6 (1995): 1049-1054.
Chicago
XIE, X., STENERSEN, T., CLAUSEN, O., BOYSEN, M."STEREOLOGIC ESTIMATION OF NUCLEAR VOLUME IN GLOTTIC SQUAMOUS-CELL CARCINOMA". Oncology Reports 2, no. 6 (1995): 1049-1054. https://doi.org/10.3892/or.2.6.1049
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