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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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November 1995 Volume 2 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November 1995 Volume 2 Issue 6

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Article

CISPLATIN, 5-FLUOROURACIL, AND LEUCOVORIN IN THE THERAPY OF ADENOCARCINOMAS OF THE PANCREAS

  • Authors:
    • DV JONES
    • SM SUGARMAN
    • AB MARKOWITZ
    • B LEVIN
    • JL ABBRUZZESE
    • DB EVANS
    • C CHARNSANGAVEJ
    • R SMITH
    • YZ PATT

  • View Affiliations / Copyright

    Affiliations: UNIV TEXAS,MD ANDERSON CANC CTR,DEPT GASTROINTESTINAL MED ONCOL & DIGEST DIS,HOUSTON,TX 77030. UNIV TEXAS,MD ANDERSON CANC CTR,DEPT SURG ONCOL,HOUSTON,TX 77030. UNIV TEXAS,MD ANDERSON CANC CTR,DEPT DIAGNOST RADIOL,HOUSTON,TX 77030. SUNY STONY BROOK,DEPT MED ONCOL,STONY BROOK,NY 11794.
  • Pages: 1121-1123
    |
    Published online on: November 1, 1995
       https://doi.org/10.3892/or.2.6.1121
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Abstract

Pancreatic cancer is resistant to most chemotherapeutic regimens. Based upon evidence of synergy between 5-fluorouracil (5-FU) and cisplatin (CDDP), and of enhanced 5-FU activity in the presence of leucovorin in other neoplasms, a phase II study of CDDP, 5-FU, and leucovorin was conducted to determine the efficacy of this regimen in patients with unresectable adenocarcinomas of the pancreas. Nineteen patients were enrolled, and all were evaluable for toxicity and response. One complete and two partial responses were observed (15.8%). Adverse effects were reversible and tolerable. This regimen has limited activity against pancreatic cancer, and cannot be recommended as standard therapy in this disease.

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Copy and paste a formatted citation
Spandidos Publications style
JONES D, SUGARMAN S, MARKOWITZ A, LEVIN B, ABBRUZZESE J, EVANS D, CHARNSANGAVEJ C, SMITH R and PATT Y: CISPLATIN, 5-FLUOROURACIL, AND LEUCOVORIN IN THE THERAPY OF ADENOCARCINOMAS OF THE PANCREAS. Oncol Rep 2: 1121-1123, 1995.
APA
JONES, D., SUGARMAN, S., MARKOWITZ, A., LEVIN, B., ABBRUZZESE, J., EVANS, D. ... PATT, Y. (1995). CISPLATIN, 5-FLUOROURACIL, AND LEUCOVORIN IN THE THERAPY OF ADENOCARCINOMAS OF THE PANCREAS. Oncology Reports, 2, 1121-1123. https://doi.org/10.3892/or.2.6.1121
MLA
JONES, D., SUGARMAN, S., MARKOWITZ, A., LEVIN, B., ABBRUZZESE, J., EVANS, D., CHARNSANGAVEJ, C., SMITH, R., PATT, Y."CISPLATIN, 5-FLUOROURACIL, AND LEUCOVORIN IN THE THERAPY OF ADENOCARCINOMAS OF THE PANCREAS". Oncology Reports 2.6 (1995): 1121-1123.
Chicago
JONES, D., SUGARMAN, S., MARKOWITZ, A., LEVIN, B., ABBRUZZESE, J., EVANS, D., CHARNSANGAVEJ, C., SMITH, R., PATT, Y."CISPLATIN, 5-FLUOROURACIL, AND LEUCOVORIN IN THE THERAPY OF ADENOCARCINOMAS OF THE PANCREAS". Oncology Reports 2, no. 6 (1995): 1121-1123. https://doi.org/10.3892/or.2.6.1121
Copy and paste a formatted citation
x
Spandidos Publications style
JONES D, SUGARMAN S, MARKOWITZ A, LEVIN B, ABBRUZZESE J, EVANS D, CHARNSANGAVEJ C, SMITH R and PATT Y: CISPLATIN, 5-FLUOROURACIL, AND LEUCOVORIN IN THE THERAPY OF ADENOCARCINOMAS OF THE PANCREAS. Oncol Rep 2: 1121-1123, 1995.
APA
JONES, D., SUGARMAN, S., MARKOWITZ, A., LEVIN, B., ABBRUZZESE, J., EVANS, D. ... PATT, Y. (1995). CISPLATIN, 5-FLUOROURACIL, AND LEUCOVORIN IN THE THERAPY OF ADENOCARCINOMAS OF THE PANCREAS. Oncology Reports, 2, 1121-1123. https://doi.org/10.3892/or.2.6.1121
MLA
JONES, D., SUGARMAN, S., MARKOWITZ, A., LEVIN, B., ABBRUZZESE, J., EVANS, D., CHARNSANGAVEJ, C., SMITH, R., PATT, Y."CISPLATIN, 5-FLUOROURACIL, AND LEUCOVORIN IN THE THERAPY OF ADENOCARCINOMAS OF THE PANCREAS". Oncology Reports 2.6 (1995): 1121-1123.
Chicago
JONES, D., SUGARMAN, S., MARKOWITZ, A., LEVIN, B., ABBRUZZESE, J., EVANS, D., CHARNSANGAVEJ, C., SMITH, R., PATT, Y."CISPLATIN, 5-FLUOROURACIL, AND LEUCOVORIN IN THE THERAPY OF ADENOCARCINOMAS OF THE PANCREAS". Oncology Reports 2, no. 6 (1995): 1121-1123. https://doi.org/10.3892/or.2.6.1121
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