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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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May-2026 Volume 55 Issue 5

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Review Open Access

Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review)

  • Authors:
    • Zidong Xia
    • Huishan Zhai
    • Lei Zheng
    • Cheng Wang
  • View Affiliations / Copyright

    Affiliations: Department of Pediatric Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China
    Copyright: © Xia et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 90
    |
    Published online on: March 9, 2026
       https://doi.org/10.3892/or.2026.9095
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Abstract

Neuroblastoma (NB) is a prevalent malignant tumor in pediatric populations, accounting for 10-15% of childhood cancer-related deaths. Standard treatments include surgery, radiotherapy and chemotherapy; however, in recent years, immunotherapy and targeted therapies have also demonstrated encouraging outcomes, particularly for high-risk NB cases. Despite these advances, more than one-third of patients either fail to respond to immunotherapy or eventually develop therapeutic resistance, highlighting the need to further explore the molecular mechanisms driving NB and to develop novel therapeutic approaches. Notably, dysregulated long non-coding RNA (lncRNA) expression is closely associated with NB prognosis, early diagnosis and therapeutic responsiveness. The present review systematically summarizes the molecular mechanisms by which lncRNAs contribute to NB development and progression, and provides an updated overview of their emerging clinical applications as diagnostic, prognostic and therapeutic targets. The current study may offer valuable insights into the future development of lncRNA-based precision diagnostic and therapeutic strategies for NB.

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Copy and paste a formatted citation
Spandidos Publications style
Xia Z, Zhai H, Zheng L and Wang C: Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review). Oncol Rep 55: 90, 2026.
APA
Xia, Z., Zhai, H., Zheng, L., & Wang, C. (2026). Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review). Oncology Reports, 55, 90. https://doi.org/10.3892/or.2026.9095
MLA
Xia, Z., Zhai, H., Zheng, L., Wang, C."Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review)". Oncology Reports 55.5 (2026): 90.
Chicago
Xia, Z., Zhai, H., Zheng, L., Wang, C."Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review)". Oncology Reports 55, no. 5 (2026): 90. https://doi.org/10.3892/or.2026.9095
Copy and paste a formatted citation
x
Spandidos Publications style
Xia Z, Zhai H, Zheng L and Wang C: Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review). Oncol Rep 55: 90, 2026.
APA
Xia, Z., Zhai, H., Zheng, L., & Wang, C. (2026). Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review). Oncology Reports, 55, 90. https://doi.org/10.3892/or.2026.9095
MLA
Xia, Z., Zhai, H., Zheng, L., Wang, C."Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review)". Oncology Reports 55.5 (2026): 90.
Chicago
Xia, Z., Zhai, H., Zheng, L., Wang, C."Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review)". Oncology Reports 55, no. 5 (2026): 90. https://doi.org/10.3892/or.2026.9095
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