Treatment results and long-term follow-up in stage I seminoma patients.

  • Authors:
    • G Hofmockel
    • M Theiss
    • A Gruss
  • View Affiliations

  • Published online on: January 1, 1996     https://doi.org/10.3892/or.3.1.107
  • Pages: 107-110
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Abstract

Between 1979 and 1992 seventy-nine patients with seminoma were treated at our institution, 62 of them with stage I. The mean follow-up time was 6.0 years (range: 36 months to 14 years). Preoperatively, serum beta human chorionic gonadotropin (beta-HCG) was elevated in 12 cases (19%) without prognostic significance. In addition to orchiectomy, 57 patients with stage I seminoma of the testis received adjuvant radiotherapy (mean dose: 33 Gy). Two patients were treated with primary retroperitoneal lymph node dissection (RPLND) and one patient with cisplatin-based chemotherapy. In 2 cases a surveillance strategy was used. Three patients (5%) had a relapse of the seminoma (2 in the retroperitoneum and one suprainguinally). The time interval between orchiectomy and relapse was 5 to 60 months. Salvage treatment consisted of chemotherapy and RPLND in 2 patients and chemotherapy and resection of the suprainguinal recurrent mass in one patient, and was successful in all 3 patients. A total of 60 patients evaluated (100%) are still alive with no evidence of disease. In conclusion, adjuvant radiotherapy is considered the routine treatment in seminomas stage I despite studies with a 'wait and watch' policy or a carboplatin monotherapy.

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January 1996
Volume 3 Issue 1

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Hofmockel G, Theiss M and Gruss A: Treatment results and long-term follow-up in stage I seminoma patients.. Oncol Rep 3: 107-110, 1996.
APA
Hofmockel, G., Theiss, M., & Gruss, A. (1996). Treatment results and long-term follow-up in stage I seminoma patients.. Oncology Reports, 3, 107-110. https://doi.org/10.3892/or.3.1.107
MLA
Hofmockel, G., Theiss, M., Gruss, A."Treatment results and long-term follow-up in stage I seminoma patients.". Oncology Reports 3.1 (1996): 107-110.
Chicago
Hofmockel, G., Theiss, M., Gruss, A."Treatment results and long-term follow-up in stage I seminoma patients.". Oncology Reports 3, no. 1 (1996): 107-110. https://doi.org/10.3892/or.3.1.107