Ondansetron (OND) vs granisetron (GRA) in the control of chemotherapy induced acute emesis

  • Authors:
    • V Leonardi
    • E Iannito
    • M Meli
    • S Palmeri
  • View Affiliations

  • Published online on: September 1, 1996     https://doi.org/10.3892/or.3.5.919
  • Pages: 919-923
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Abstract

We enrolled 118 chemonaive cancer patients (pts) to receive OND i.v. dl or GRA i.v. dl. Seventy of the 118 pts received moderately emetogenic (ME) chemotherapy (140 cycles), while 48 received highly emetogenic (HE) chemotherapy (93 cycles). Therapeutic success was obtained in 89% (OND) vs 94% (GRA) cycles of HE and in 96.8% (OND) vs 95.6% (GRA) cycles of ME. The main toxicities were headache (24%, OND; 23%, GRA); light-headedness (13%, OND; 18%, GRA); constipation (11%, OND; 6%, GRA). In conclusion, we think that OND and GRA are effective and the two drugs are equally active and toxic.

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September 1996
Volume 3 Issue 5

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Leonardi V, Iannito E, Meli M and Palmeri S: Ondansetron (OND) vs granisetron (GRA) in the control of chemotherapy induced acute emesis. Oncol Rep 3: 919-923, 1996
APA
Leonardi, V., Iannito, E., Meli, M., & Palmeri, S. (1996). Ondansetron (OND) vs granisetron (GRA) in the control of chemotherapy induced acute emesis. Oncology Reports, 3, 919-923. https://doi.org/10.3892/or.3.5.919
MLA
Leonardi, V., Iannito, E., Meli, M., Palmeri, S."Ondansetron (OND) vs granisetron (GRA) in the control of chemotherapy induced acute emesis". Oncology Reports 3.5 (1996): 919-923.
Chicago
Leonardi, V., Iannito, E., Meli, M., Palmeri, S."Ondansetron (OND) vs granisetron (GRA) in the control of chemotherapy induced acute emesis". Oncology Reports 3, no. 5 (1996): 919-923. https://doi.org/10.3892/or.3.5.919